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Your search for Pain Medication returned 19 results. Search again.


Long-Term Follow-Up of Medication-Assisted Treatment for Addiction to Pain Relievers Yields “Cause for Optimism”

In the first long-term follow-up of patients treated with buprenorphine/naloxone for addiction to opioid pain relievers, half reported that they were abstinent from the drugs 18 months after starting the therapy.


Study Points to Individualized Therapy for Opioid Addiction

Trial participants who were addicted to opioid painkillers and did not inject drugs stayed in treatment longer and achieved better outcomes than those who were addicted to heroin or injected drugs.


Patients Addicted to Opioid Painkillers Achieve Good Results With Outpatient Detoxification

A significant portion of individuals who are addicted to opioid painkillers may initiate and maintain abstinence with a brief but intensive outpatient detoxification treatment followed by opioid antagonist therapy using naltrexone.


Although Relatively Few, “Doctor Shoppers” Skew Opioid Prescribing

One out of every 143 U.S. patients who received a prescription for an opioid painkiller in 2008 obtained prescriptions from multiple physicians in a pattern that suggests misuse or abuse of the drugs.


Problem Behaviors Can Signal Risk in Prescribing Opioids to Teens

Researchers found that 1 in 8 high school seniors had used a prescription opioid nonmedically, and 70 percent of these teens had compounded the attendant risk by co-ingesting an opioid with one or more other drugs. Nonmedical opioid use was significantly more prevalent among whites than among African Americans or Hispanics.


Oxycodone Vaccine Passes Early Tests

A new vaccine hindered the often-abused prescription opioids oxycodone and hydrocodone from entering the brain and suppressed one of the drugs’ signature central nervous system effects. The findings warrant continued development of the vaccine as a potential aid in the treatment of oxycodone and hydrocodone abuse and dependence.


Thoughts of Suicide May Persist Among Nonmedical Prescription Opiate Users

People who use prescription opiates nonmedically are more likely to consider suicide than those who use these medications only appropriately or not at all. A recent NIDA-supported study also disclosed that the risk for suicidal thoughts remains elevated after cessation of use.


Adolescent Cigarette, Alcohol Use Declines as Marijuana Use Rises

Fewer teens are using cigarettes, alcohol, and most illicit drugs, according to NIDA’s latest Monitoring the Future study. Troubling  trends persist in marijuana use, however, and nonmedical prescription drug use remains a concern.

NIDA @ Work

Q&A: Dr. David Thomas

NIDA Program Officer Dr. David Thomas speaks about the intertwined problems of pain and prescription opioid abuse, as well as the research supported by NIDA and the National Institutes of Health to address these problems.


Potential Pain Medication Targets Peripheral Nerves

Researchers report a significant advance in the search for medications that can suppress pain but avoid opioids’ abuse potential and other undesirable CNS effects. A new compound reduces mouse responses in animal models of neurogenic and chronic inflammatory (e.g., arthritic) pain. The compound, called UB937, enhances the natural pain-killing activity of the neurotransmitter anandamide, and exerts its analgesic effects entirely in peripheral tissues, without entering the brain.


Few Teens With Prescription Opioid Use Disorders Receive Treatment

Fewer than 12 percent of adolescents who meet diagnostic criteria for prescription opioid abuse or dependence receive any treatment, according to an analysis of data from the 2005 to 2008 National Survey on Drug Use and Health. The most common reason the adolescents gave for not receiving treatment was their lack of perceived need for it.


Some Teens Reporting Nonmedical Use of Prescriptions Develop Disorders

Reports teen drug abuse based on 2006-2007 data from a national survey on drug use and health and compares differences by gender.

Basic Science Discoveries Yield Novel Approaches to Analgesia

Describes research to develop new compounds that match or exceed the pain relief provided by opioids while avoiding their shortcomings.


Morphine Speeds AIDS Onset in Monkeys

Highlights the work of investigators who discovered key ways in which morphine may accelerate the progression of AIDS in animal studies.

Basic Science

Morphine-Induced Immunosuppression, From Brain to Spleen

Reports on scientists who pinpointed the biochemical trigger from morphine that sets off a chain reaction that inhibits an immune cell that is key in fighting viruses and cancer.


Alcohol Abuse Makes Prescription Drug Abuse More Likely

Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.

Basic Science

Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.


Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats

Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

Bulletin Board

Meeting Reviews Progress On Prescription Opioid Misuse

Describes a meeting of researchers and clinicians who gathered to discuss the challenges in balancing appropriate pain treatment with efforts to minimize prescription opioid misuse.
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