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Basic Science

Stress-Induced Enzyme Compounds Methamphetamine Neurotoxicity

Ketoprofen, an anti-inflammatory agent commonly prescribed to treat arthritis, reduces neuronal damage in rats that have been exposed to chronic stress and methamphetamine. If this finding of a recent NIDA-supported study extrapolates to humans, anti-inflammatory medications may gain a place in the treatment of methamphetamine addiction.

Treatment

Staff Stress Affects Patients’ Engagement in Therapy

Several factors contribute to treatment professionals’ stress and burnout, including how much influence they feel they have in their organization and their caseload. Surprisingly, a NIDA-supported study found that the link between staff stress and burnout was weaker in programs with higher patient caseloads than those with lower caseloads. In addition, program administrators can help counselors reduce their stress by giving them a voice in organizational policies and procedures.  

Treatment

High Rates of Job Leaving Among Addiction Counselors

Substance abuse counselors and clinical supervisors disclosed high job turnover rates in a survey of 27 treatment organizations.

Treatment

Medication Reduces Rats' Return to Methamphetamine Seeking

Reports on a new medication strategy under investigated in animal studies that shows promise for preventing relapse to drug abuse.

Treatment

Treatment Dropout Linked With Elevated Stress Response

Summarizes a study to determine whether a stress-related biological marker in saliva can predict how long a drug user will remain in treatment.

Bulletin Board

Three Scientists Join Advisory Council

Announces three new NIDA National Advisory Council on Drug Abuse members and describes their drug abuse and addiction research experience.
Director's Perspective

Substance Abuse Among Troops, Veterans, and Their Families

Highlights the need for research to assess and find solutions to a potential rise in substance abuse among service men and women, veterans, and their families.

Treatment

Lofexidine May Enhance Naltrexone Efficacy

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

Director's Perspective

Addiction and Co-Occurring Mental Disorders

Presents an overview of the research underway to investigate medication and behavioral therapies for co-occurring disorders.

Studies Focus on Acculturation and Hispanic Youth

Summarizes a study that analyzes factors associated with the risk of drug addiction among 19- to 21-year-old Hispanic women born in the United States as compared with immigrants.
Basic Science

Stress Response May Underlie African- Americans' Reduced Pain Tolerance

Summarizes research suggesting a physiological difference as the explanation for African-Americans' reported low tolerance for pain.

NIDA Notes

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