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NIDA Notes keeps you up to date on research advances in the causes, consequences, prevention, and treatment of drug abuse and addiction and HIV/AIDS.

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Childhood Maltreatment Changes Cortical Network Architecture and May Raise Risk for Substance Use (November 2015)

Young adults who had been maltreated as children differed from others who had not been maltreated in the connectivity of nine cortical regions. The differences could compromise the maltreated group’s basic social perceptual skills, ability to maintain a healthy balance between introversion and extroversion, and ability to self-regulate their emotions and behavior.

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Digital Addiction Therapies Affirm Promise in Replication and Large Trial (November 2015)

Two computerized programs improved outcomes when they were used to supplement or partially replace in-person behavioral therapy for drug addiction in recent NIDA-sponsored trials.

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Narrative of Discovery: Can Magnets Treat Cocaine Addiction? (September 2015)

Two researchers share their reasons for researching transcranial magnetic stimulation (TMS) for treating cocaine addiction, and describe challenges to moving forward this potentially promising therapy.

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Why Take a Drug That No Longer Gives Pleasure? (September 2015)

In mice, a cocaine-induced imbalance in the activity of two key populations of neurons in the reward system persists for a longer period after repeated exposure to the drug. For long-term users, this change could both weaken the cocaine “high” and strengthen the compulsion to seek the drug.

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Teen Foster Care Program Reduces Drug Use in Early Adulthood (September 2015)

New findings from a follow-up to a NIDA-supported trial indicate that the benefits of Multidimensional Treatment Foster Care extend to a reduction in illegal drug use in young adulthood.

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THC Hampers Spatial Memory Development in Young Monkeys (September 2015)

Adolescent monkeys that were exposed to THC fell progressively further behind THC-free monkeys in their ability to recall the location of an object after a brief delay.

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Brain Imaging Predicts Relapse to Cocaine (September 2015)

A NIDA-supported study has found that a cocaine-addicted person’s chance of managing 1 whole year of abstinence correlates with activity levels in these impaired motivational and decision-making brain areas.

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A Rapid Teen Substance Use Screening Tool for Clinicians (July 2015)

Answers to three simple questions can help a busy health care provider flag a teen’s problematic use of alcohol, tobacco, or marijuana.

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Electronic Questionnaire Quickly Rates Teens’ Substance Use (July 2015)

With a few simple questions, a new screening tool detects whether a teen is likely to have a mild-to-moderate or a severe substance use disorder.

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Study Ranks Recovery Assets in Cocaine Addiction (July 2015)

A can-do attitude, ability to cope with potential triggers for drug use, readiness to change, and participation in self-help programs are major assets for people trying to recover from cocaine addiction.


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