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Vaccine Designed to Keep Cocaine Out of the Brain Description

This is a pair of diagrams that show the paths of cocaine molecules to the brain Vaccine Designed to Keep Cocaine Out of the Brain: Under normal conditions, cocaine molecules (shown as gold circles) easily cross from the blood into the brain (top diagram). A series of vaccines, however, stimulates patients' immune systems to produce cocaine antibodies (red Ys) that attach to molecules of the drug and prevent them from reaching the brain (bottom diagram).

This pair of diagrams shows the difference between a patient's immune system with and without protection from antibodies against cocaine. In the unprotected immune system, the normal condition, cocaine molecules enter the bloodstream and then cross unimpeded from the blood into the brain. In the protected immune system, a series of vaccines has stimulated the patient's immune system to produce cocaine antibodies in the blood. They attach to most of the molecules of cocaine and prevent them from reaching the brain.

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