A meta-analysis of 13 genome-wide association studies of African Americans’ smoking patterns confirms the significance of genetic variation in region 15q25.1. The analysis also tentatively implicates several genome locations that have not previously been associated with smoking behaviors.
Electronic cigarettes (also called e-cigarettes or electronic nicotine delivery systems) are smokeless, battery operated devices designed to deliver nicotine with flavorings or other chemicals to the lungs of users without burning tobacco (the usual source of nicotine). They are typically manufactured to resemble regular tobacco cigarettes, cigars, pipes, or even everyday items like pens or USB memory sticks. More than 250 different e-cigarette brands are currently on the market.
Women who reached their majority in states with policies that restricted teens’ access to tobacco products were less likely to smoke from ages 18-34 than women in states without those policies. The research did not demonstrate that the policies had a comparable impact on men’s smoking.
Dr. Marilyn Huestis of NIDA’s Intramural Research Program talks about conducting research on drug effects with human subjects, developing tests to help law enforcement identify drugged drivers, and an assay to help identify children whose prenatal exposure to anti-HIV drugs may put them at risk for adverse developmental outcomes.
Men benefit more than women from nicotine replacement therapy for smoking cessation because nicotine affects a key neuroreceptor differently in the two sexes, a NIDA-sponsored study suggests. The findings highlight the need for alternative therapies for women smokers, and point to the female hormone progesterone as a potential therapeutic target.
Fewer teens are using cigarettes, alcohol, and most illicit drugs, according to NIDA’s latest Monitoring the Future study. Troubling trends persist in marijuana use, however, and nonmedical prescription drug use remains a concern.