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A Genetic Nexus of Obesity and Smoking

octubre del 2014

Research shows that some gene variants that influence body mass index also shape smoking behaviors.

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New Approach Uses Immune Cells To Deliver Anti-HIV Medications

octubre del 2014

Nano-antiretroviral therapy (nano-ART) turns macrophages—one of the very cell types that HIV uses to replicate and spread through the body—into carriers for anti-HIV medications. The approach has the potential to make treatment for HIV easier and more effective.

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Student-Scientists Present Award-Winning Research at NIDA

agosto del 2014

Four high school students were honored for their work regarding e-cigarettes, the GABAA neuroreceptor, and adolescent multitasking.

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Training Workshops Boost Approval of Contingency Management

agosto del 2014

Clinicians associated with the Veterans Administration looked more favorably upon contingency management after attending training workshops on the use of the intervention. Despite being highly effective at decreasing drug use, contingency management is one of the least used among proven substance abuse treatments.

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Self-Control Protects Urban Minority Youths From Drug Use and Depressive Mood

julio del 2014

Interventions that bolster self-control in childhood and early adolescence might shield ethnic and racial minority adolescents and young adults from the burden of both drug use and depressive mood.

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Among High School Seniors, Driving After Marijuana Use Surpasses Drunk Driving

julio del 2014

Within the 2 weeks prior to responding to a nationwide survey, 28 percent of high school seniors were in a vehicle whose driver had been using marijuana or another illicit drug, or had drunk 5 or more alcoholic drinks.

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Dr. Antonello Bonci Q & A: Lighting Up the Brain To Shut Down Cocaine Seeking

julio del 2014

The Scientific Director of NIDA’s Intramural Research Program talks about switching off animals’ compulsive cocaine seeking by optogenetically activating the prefrontal cortex, and the implications of this work for people. In an accompanying podcast, Dr. Bonci walks viewers through experiments that showed that prefrontal cortex activity levels may constitute a simple switch controlling whether or not animals compulsively seek cocaine.

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Gene Variants Reduce Opioid Risks

junio del 2014

Two recent studies suggest that genotyping may enable clinicians to base therapies on individual patients’ potential responsiveness to opioid drugs’ therapeutic effects and vulnerability to their harmful effects.

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New Insight Into How Cues Cause Relapse to Cocaine

mayo del 2014

A brain response occurs in the nucleus accumbens when rats encounter a cue that they associate with previous cocaine self-administration, but not a cue associated with a pleasurable non-drug experience. Moreover, the response correlates in time and intensity with the animals’ cue-induced relapse to cocaine-seeking.

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Device Detects Marijuana in Breath Hours After Smoking

mayo del 2014

Driving under the influence of marijuana is a dangerous public health concern. NIDA researchers have discovered that breath expelled into a Breathalyzer-style collection device contained measurable amounts of THC for up to 2 hours after participants in a recent clinical trial smoked the drug.

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