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California Reaped Large Savings by Diverting Drug-Using Offenders Into Treatment

febrero del 2014

California’s Proposition 36, which allows qualified drug offenders to enter substance use treatment rather than go to jail or prison, saved the state close to $100 million in its first year.

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Intervention Strengthens American Indian Teen Mothers’ Parenting

febrero del 2014

Teen mothers on three American Indian reservations improved on several measures of parenting after participating in Family Spirit, a home-visiting intervention developed with NIDA support. At 12 months postpartum, the women’s children exhibited reduced rates of emotional difficulties predicting later drug abuse and other behavioral problems. Infants at highest risk—those whose mothers had histories of drug abuse—benefited the most.

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Stress-Induced Enzyme Compounds Methamphetamine Neurotoxicity

enero del 2014

Ketoprofen, an anti-inflammatory agent commonly prescribed to treat arthritis, reduces neuronal damage in rats that have been exposed to chronic stress and methamphetamine. If this finding of a recent NIDA-supported study extrapolates to humans, anti-inflammatory medications may gain a place in the treatment of methamphetamine addiction.

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HIV Infection Accelerates Hepatitis C–Related Liver Fibrosis

enero del 2014

Study patients with HIV­­–hepatitis C coinfection progressed to successive degrees of severity of liver fibrosis 9 years sooner than those infected with HCV alone. Further findings from the study suggest that suppressing HIV with antiretroviral medications may slow HCV-related liver fibrosis.

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Prefrontal Cortex Stimulation Stops Compulsive Drug Seeking in Rats

enero del 2014

Researchers have shut down laboratory rats’ compulsive cocaine seeking by stimulating an area of the animals’ prefrontal cortex. The finding raises the possibility that stimulating neurons in this brain area may weaken or break cocaine’s grip on the behavior of people who are addicted to the drug.

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American Researcher Dr. Charles O’Brien Knighted by French Government

enero del 2014

NIDA grantee Dr. O’Brien was honored for his “exemplary personal commitment to French‒American relations as symbolized by … exceptional cooperation in science and in public health.”

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Dr. Evan D. Kharasch Joins the Institute of Medicine

diciembre del 2013

Dr. Kharasch is a NIDA-funded researcher known for a broad range of research into how drugs are metabolized in the body.

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Medications That Treat Opioid Addiction Do Not Impair Liver Health

diciembre del 2013

A trial of buprenorphine/naloxone (Bup/Nx) showed no evidence that the medicine was associated with liver damage. The drug gave results similar to those of methadone. The study data indicate that although most patients can be treated safely with either methadone or Bup/Nx without major concern for liver injury, clinicians are advised to continue to monitor the liver health of their patients who are on methadone or Bup/Nx therapy.

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Study Finds Genetic Influence on African Americans’ Smoking

noviembre del 2013

A meta-analysis of 13 genome-wide association studies of African Americans’ smoking patterns confirms the significance of genetic variation in region 15q25.1. The analysis also tentatively implicates several genome locations that have not previously been associated with smoking behaviors.

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Naltrexone Implant Outperforms Daily Pill in Russian Trial

noviembre del 2013

More than half of heroin-addicted patients treated with naltrexone via an implanted delivery device maintained abstinence throughout a 6-month clinical trial in Saint Petersburg, Russia. The implant device, which releases a steady dose of naltrexone continuously for 2 months, averted relapse to heroin use three times as effectively as daily oral doses of the medication.

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