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NIDA Notes Articles: Genetics

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Ethnic Groups Have Contrasting Genetic Risks for Nicotine Addiction

octubre del 2009

Describes research exploring differences and similarities in the genetic profiles of African-Americans and European-Americans who are heavy smokers.

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Manic Mice Show Heightened Sensitivity to Rewards

octubre del 2009

Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.

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New Technique Links 89 Genes to Drug Dependence

septiembre del 2008

Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.

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Mice With Genetic Alteration Eschew Cocaine

junio del 2008

Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

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Cocaine Can Mobilize Stored Dopamine

Marzo del 2008

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Chromosome 17 Harbors Opioid Dependence Genes

Marzo del 2008

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

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Epigenetics: The Promise of a New Science

Marzo del 2008

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

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Genes and Smoking

abril del 2007

Reports on the research underway to identify gene variations associated with nicotine addiction and the interaction of genetic makeup, experiences, and surroundings to addiction.

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