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NIDA Notes Articles: Genetics

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Genes and Smoking

abril del 2007

Reports on the research underway to identify gene variations associated with nicotine addiction and the interaction of genetic makeup, experiences, and surroundings to addiction.

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Genetic Overlap Between Substance Abuse and Bipolar Disorder

abril del 2010

Describes a literature analysis reporting on the prevalence of people with bipolar disorder who also have a substance use disorder and discusses the genetic link that may contribute to this comorbidity.

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Individual Differences in Decisionmaking Style May Predict Teen Problems

diciembre del 2011

Reports on the relative influence of genes versus environment on adolescents’ choices that involve delayed gratification.

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Male Rats’ Cocaine Exposure Affects Their Offspring’s Drug Responses

agosto del 2013

In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.

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Manic Mice Show Heightened Sensitivity to Rewards

octubre del 2009

Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.

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Mice With Genetic Alteration Eschew Cocaine

junio del 2008

Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

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New Technique Links 89 Genes to Drug Dependence

septiembre del 2008

Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.

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NIDA Grantee Wins Prize for Genetics Web Sites

diciembre del 2010
Announces the recipient of an award for online resources in education, Dr. Louisa Stark, who developed two interactive Web sites on genetics.

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NIDA's 35th Anniversary: Science Focused on Solutions

diciembre del 2009

Commemorates NIDA’s 35th anniversary and highlights some of the major accomplishments since the Institute’s inception in 1974.

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Parental Supervision and Genetics Interact To Influence Nicotine Addiction

diciembre del 2010

Reviews research indicating that both parental influence and certain genes interact to influence nicotine addiction and that parental monitoring may play a role in reducing risk.

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