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NIDA Notes Articles: Genetics

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A Genetic Nexus of Obesity and Smoking

octubre del 2014

Research shows that some gene variants that influence body mass index also shape smoking behaviors.

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Chromosome 17 Harbors Opioid Dependence Genes

Marzo del 2008

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

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Cocaine Can Mobilize Stored Dopamine

Marzo del 2008

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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DESPR Identifies Drug Abuse Trends and Seeks Solutions

noviembre del 2009
Discusses the work of NIDA’s Division of Epidemiology, Services and Prevention Research, organized to track drug use and provide empirically based information for researchers and service providers.

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Dr. David Jentsch Receives the 2011 Waletzky Memorial Award

julio del 2012
Dr. J. David Jentsch is the recipient of the 2011 Jacob P. Waletzky Memorial Award for Innovative Research in Drug Addiction and Alcoholism. Dr. Jentsch and colleagues at the University of California, Los Angeles, are studying genetic and neurochemical factors that influence individual differences in inhibitory control.

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Dr. Joni Rutter Q&A: How Basic Science Is Tackling Addiction

mayo del 2014

One of NIDA’s goals is to try to understand the individual differences that contribute to whether or not someone who takes a drug will become addicted to it. Dr. Rutter’s research focuses on three types of differences: Environmental, developmental, and genetic and epigenetic.

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Epigenetics: The Promise of a New Science

Marzo del 2008

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

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Ethnic Groups Have Contrasting Genetic Risks for Nicotine Addiction

octubre del 2009

Describes research exploring differences and similarities in the genetic profiles of African-Americans and European-Americans who are heavy smokers.

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Gene Influences Impact of Maternal Smoking on Children's Behavioral Problems

julio del 2011
Describes research showing that the combination of prenatal smoking exposure and specific genes increases children’s and adolescent’s risk for behavior problems.

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Gene Variants Reduce Opioid Risks

junio del 2014

Two recent studies suggest that genotyping may enable clinicians to base therapies on individual patients’ potential responsiveness to opioid drugs’ therapeutic effects and vulnerability to their harmful effects.

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