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NIDA Notes Articles: Ciencia de la adicción

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Immune System Plays Unexpected Role in Brain Development

septiembre del 2008

Describes research findings demonstrating that the immune system participates in the shaping of brain circuits during a child's development, a finding that may shed light on the origins of neurodegenerative diseases.

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Impacts of Drugs on Neurotransmission

octubre del 2007

Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.

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In Animals, Receptor Puts Brakes on Nicotine Consumption

marzo del 2012

New research suggests that differences in tobacco consumption reflect, in part, differences in the functional efficacy of a specific type of receptor in a pathway of the brain. In animal studies, nicotinic acetylcholine receptors with the α5 subunit played a key role in producing aversive responses to nicotine, thereby dissuading further consumption of the drug.

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Investigators Map Functional Networks in the Rat Brain

junio del 2012

Researchers have mapped the fundamental functional organization of the rat brain and shown that it resembles that of the human brain.

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Long-Term Cocaine Abuse Linked With Impaired Heart Function

marzo del 2008
Summarizes research on the effects of long-term regular cocaine abuse on the cardiovascular system in African Americans.

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Long-Term Cocaine Self-Administration Depresses Brain Activity

diciembre del 2008

Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction

abril del 2009

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Lower Levels of Dopamine-Regulating Receptors Among Novelty Seekers

octubre del 2010

Describes research results reporting that people who favor novelty have lower-than-average availability of a receptor that inhibits dopamine's release from neurons, which likely stimulates the activity of reward circuits.

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Methamphetamine Abuse Alters Response to Facial Cues

octubre del 2009

Highlights research showing methamphetamine abusers may have more difficulty than nonabusers in responding with empathy and self-control to people who are experiencing intense emotions.

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Methamphetamine Abusers Show Increased Distractibility

abril del 2009

Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.


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