In English
NIDA

NIDA Notes Articles: Basic Science

NIDA Notes Category Graphic

Male Rats’ Cocaine Exposure Affects Their Offspring’s Drug Responses

agosto del 2013

In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.

NIDA Notes Category Graphic

Stimulants in “Bath Salts” Produce Effects Similar to MDMA

agosto del 2013

Mephedrone and methylone, two stimulants commonly found in designer drugs such as “bath salts,” act on the brain much like MDMA (Ecstasy).

NIDA Notes Category Graphic

Study Finds Genetic Influence on African Americans’ Smoking

noviembre del 2013

A meta-analysis of 13 genome-wide association studies of African Americans’ smoking patterns confirms the significance of genetic variation in region 15q25.1. The analysis also tentatively implicates several genome locations that have not previously been associated with smoking behaviors.

NIDA Notes Category Graphic

Prefrontal Cortex Stimulation Stops Compulsive Drug Seeking in Rats

enero del 2014

Researchers have shut down laboratory rats’ compulsive cocaine seeking by stimulating an area of the animals’ prefrontal cortex. The finding raises the possibility that stimulating neurons in this brain area may weaken or break cocaine’s grip on the behavior of people who are addicted to the drug.

NIDA Notes Category Graphic

Stress-Induced Enzyme Compounds Methamphetamine Neurotoxicity

enero del 2014

Ketoprofen, an anti-inflammatory agent commonly prescribed to treat arthritis, reduces neuronal damage in rats that have been exposed to chronic stress and methamphetamine. If this finding of a recent NIDA-supported study extrapolates to humans, anti-inflammatory medications may gain a place in the treatment of methamphetamine addiction.

NIDA Notes Category Graphic

Methamphetamine Alters Brain Structures, Impairs Mental Flexibility

Marzo del 2014

Methamphetamine alters brain structures involved in decision-making and impairs the ability to suppress habitual behaviors that have become useless or counterproductive. The two effects were correlated, indicating that the structural change underlies the decline in mental flexibility.

Pages

NIDA Notes

Tags

Drug Topics

Drugs of Abuse

Population Groups

Related Topics

Toma el reto nacional sobre el coeficiente intelectual (CI) sobre las drogas