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NIDA Notes Articles: Basic Science

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Methamphetamine Restricts Fetal Growth, Increases Lethargy in Newborns

junio del 2008

Reports on research showing that newborns whose mothers abused methamphetamine during pregnancy showed lower rates of fetal growth as compared with unexposed newborns.

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Immune System Plays Unexpected Role in Brain Development

septiembre del 2008

Describes research findings demonstrating that the immune system participates in the shaping of brain circuits during a child's development, a finding that may shed light on the origins of neurodegenerative diseases.

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Optical Technologies Expand Vistas Into the Brain

septiembre del 2008

Describes new tools under development, including one to visualize cells deep in the brain and another one that remotely activates brain cells.

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New Technique Links 89 Genes to Drug Dependence

septiembre del 2008

Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.

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Imaging Studies Elucidate Neurobiology of Cigarette Craving

diciembre del 2008

Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.

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Long-Term Cocaine Self-Administration Depresses Brain Activity

diciembre del 2008

Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.

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Brain Proteins Differ in Cocaine-Overdose Victims

diciembre del 2008

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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Adolescent Rats Self-Administer More Nicotine Than Adults

abril del 2009

Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.

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Methamphetamine Abusers Show Increased Distractibility

abril del 2009

Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.

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Cocaine Locks Rats Into Unrewarding Behaviors

abril del 2009

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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