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NIDA Notes Articles: Treatment

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Legal Pressure Increases Treatment Retention

abril del 2009

Presents data on the length of stay in substance abuse treatment among people who were in treatment as a result of legal pressure as compared with those in treatment voluntarily.

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Lofexidine May Enhance Naltrexone Efficacy

diciembre del 2008

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Medication Reduces Rats' Return to Methamphetamine Seeking

julio del 2011

Reports on a new medication strategy under investigated in animal studies that shows promise for preventing relapse to drug abuse.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

octubre del 2010

Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Medications That Treat Opioid Addiction Do Not Impair Liver Health

diciembre del 2013

A trial of buprenorphine/naloxone (Bup/Nx) showed no evidence that the medicine was associated with liver damage. The drug gave results similar to those of methadone. The study data indicate that although most patients can be treated safely with either methadone or Bup/Nx without major concern for liver injury, clinicians are advised to continue to monitor the liver health of their patients who are on methadone or Bup/Nx therapy.

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Methadone Reduces Rats' Cocaine Seeking

diciembre del 2008

Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Methadone Therapy in Prison Benefits Men a Year Out

noviembre del 2009

Describes clinical trial results providing evidence that methadone maintenance to men in prison can pay off in better retention in community treatment and reduced drug abuse following their release.

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Methamphetamine Abuse Undermines Dental Health

julio del 2011

Describes research that sheds light on the correlation between increased dental disease and methamphetamine abuse.

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Microneedle Milestone: One Week of Transdermal Drug Delivery

marzo del 2014

Microneedles are an innovative technique for delivering medications through the skin, a route that could particularly benefit patients receiving naltrexone therapy for opioid and alcohol dependence. Researchers have found a way to use the transdermal technique to deliver a single treatment of naltrexone that lasts for 7 days.

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Modafinil Normalizes Sleep During Early Cocaine Abstinence

diciembre del 2010

Describes a study investigating the effectiveness of modafinil in enhancing sleep among cocaine abusers who are currently abstinent.

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