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NIDA Notes Articles: Treatment

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Abstinent Smokers' Nicotinic Receptors Take More Than a Month to Normalize

octubre del 2009

Describes research revealing that for up to 6 weeks after smokers quit, their brain cells have more nicotine-binding receptors than nonsmokers, which may explain the struggle to quit.

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Alleviation of Posttraumatic Stress Disorder May Improve Addiction Treatment

abril del 2012

Women with posttraumatic stress disorder (PTSD) who abused drugs responded better to substance abuse treatment after their PTSD symptoms improved, according to a recent study, which also found that reductions in substance abuse did not ease PTSD severity

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Animal Research Advances Effort to Develop Vaccines Against Cocaine, Heroin Abuse

septiembre del 2012

New vaccines that aim to promote recovery from cocaine and heroin abuse showed promise in animal testing. Both vaccines induced rats’ immune system to produce high titers of antibodies that inhibit the target drug from reaching the brain. The rats’ behaviors when given access to the target drug indicated that the vaccines reduced the reinforcing effects that, in recovering people, can cause lapses to turn into relapses.

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Animation: Building an Anti-Drug Vaccine

diciembre del 2012

The immune system has an extraordinary ability to recognize compounds foreign to the body and eliminate them. NIDA-sponsored scientists are working to harness this ability to create vaccines that will protect individuals against the psychogenic and addictive effects of abused drugs. This animation shows one of the most promising strategies, which has already yielded partial success in producing effective vaccines against nicotine, cocaine, and other drugs.

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Antibody Fragment Removes Methamphetamine From the Brain

noviembre del 2009

Reports animal study findings on development of an antibody fragment that rapidly removes methamphetamine from the brain and discusses implications for treatment of overdose.

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Anticipation of Methadone Enhances Brain Reactivity to Heroin Cues

diciembre del 2009

Describes findings of a study revealing that images of heroin preparation and injection can incite craving and excite brain areas associated with reward-seeking even in methadone-maintained patients.

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Antiretroviral Treatment Reduces Spread of HIV Among Injection Drug Users

abril del 2012
Expanded use of antiretroviral therapy in British Columbia reduced the spread of HIV among injection drug users and others in the province.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

diciembre del 2008

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Attention to Bipolar Disorder Strengthens Substance Abuse Treatment

abril del 2010

Describes a study of participants who had both substance abuse and bipolar disorder to investigate the potential benefits of integrated group therapy for this population.

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Basic Science Discoveries Yield Novel Approaches to Analgesia

septiembre del 2008

Describes research to develop new compounds that match or exceed the pain relief provided by opioids while avoiding their shortcomings.

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Toma el reto nacional sobre el coeficiente intelectual (CI) sobre las drogas