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NIDA Notes Articles: Estimulantes

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Adolescent Cigarette, Alcohol Use Declines as Marijuana Use Rises

febrero del 2013

Fewer teens are using cigarettes, alcohol, and most illicit drugs, according to NIDA’s latest Monitoring the Future study. Troubling  trends persist in marijuana use, however, and nonmedical prescription drug use remains a concern.

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Animal Research Advances Effort to Develop Vaccines Against Cocaine, Heroin Abuse

septiembre del 2012

New vaccines that aim to promote recovery from cocaine and heroin abuse showed promise in animal testing. Both vaccines induced rats’ immune system to produce high titers of antibodies that inhibit the target drug from reaching the brain. The rats’ behaviors when given access to the target drug indicated that the vaccines reduced the reinforcing effects that, in recovering people, can cause lapses to turn into relapses.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

diciembre del 2008

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Brain Adaptation May Dampen Effects of Cocaine

octubre del 2010
Reports evidence that a cocaine-induced change in the structure of brain cells represents an adaptive response that may limit the drug’s impact.

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Brain Opioid Receptor Levels Predict Time to Cocaine Relapse

octubre del 2010
Describes study findings revealing that cocaine abusers who maintain high levels of a certain receptor in their brain during early abstinence relapse sooner than abusers whose levels drop.

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Brain Proteins Differ in Cocaine-Overdose Victims

diciembre del 2008

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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Cocaine Alters Production of Hundreds of Proteins

Marzo del 2011

Describes research findings that show that chronic cocaine abuse may change the production of many proteins in the neurons of the brain’s reward system, aiding in our understanding how the drug causes addiction.

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Cocaine Can Mobilize Stored Dopamine

Marzo del 2008

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Cocaine Locks Rats Into Unrewarding Behaviors

abril del 2009

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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Cocaine Vaccine Helps Some Reduce Drug Abuse

diciembre del 2010

Reports on the results of a clinical trial that tested the effectiveness of a cocaine vaccine designed as a therapy for cocaine abuse and plans underway for a new study of 300 patients to confirm these results.

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Toma el reto nacional sobre el coeficiente intelectual (CI) sobre las drogas