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NIDA Notes Articles: Estimulantes

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Brain Adaptation May Dampen Effects of Cocaine

octubre del 2010
Reports evidence that a cocaine-induced change in the structure of brain cells represents an adaptive response that may limit the drug’s impact.

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Brain Opioid Receptor Levels Predict Time to Cocaine Relapse

octubre del 2010
Describes study findings revealing that cocaine abusers who maintain high levels of a certain receptor in their brain during early abstinence relapse sooner than abusers whose levels drop.

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Crack Cocaine Promotes Progression of HIV Infection to AIDS

octubre del 2010
Reports on two studies showing a high prevalence of HIV infection and more rapid progression to disability and death among drug abusers.

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New Tools and Strategies to Bolster Behavioral Therapy

octubre del 2010

Reports on research investigating whether certain medications might strengthen patients' understanding and memory retention.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

octubre del 2010
Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Deep Brain Stimulation Reduces Rats' Cocaine Seeking

diciembre del 2010
Describes results from an animal study involving deep brain stimulation that holds promise as a therapy for severe cocaine addiction.

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Modafinil Normalizes Sleep During Early Cocaine Abstinence

diciembre del 2010
Describes a study investigating the effectiveness of modafinil in enhancing sleep among cocaine abusers who are currently abstinent.

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Cocaine Vaccine Helps Some Reduce Drug Abuse

diciembre del 2010

Reports on the results of a clinical trial that tested the effectiveness of a cocaine vaccine designed as a therapy for cocaine abuse and plans underway for a new study of 300 patients to confirm these results.

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Cocaine Alters Production of Hundreds of Proteins

Marzo del 2011

Describes research findings that show that chronic cocaine abuse may change the production of many proteins in the neurons of the brain’s reward system, aiding in our understanding how the drug causes addiction.

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Medication Reduces Rats' Return to Methamphetamine Seeking

julio del 2011

Reports on a new medication strategy under investigated in animal studies that shows promise for preventing relapse to drug abuse.

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