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NIDA Notes Articles: Estimulantes

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Prefrontal Cortex Stimulation Stops Compulsive Drug Seeking in Rats

enero del 2014

Researchers have shut down laboratory rats’ compulsive cocaine seeking by stimulating an area of the animals’ prefrontal cortex. The finding raises the possibility that stimulating neurons in this brain area may weaken or break cocaine’s grip on the behavior of people who are addicted to the drug.

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Stimulants in “Bath Salts” Produce Effects Similar to MDMA

agosto del 2013

Mephedrone and methylone, two stimulants commonly found in designer drugs such as “bath salts,” act on the brain much like MDMA (Ecstasy).

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Male Rats’ Cocaine Exposure Affects Their Offspring’s Drug Responses

agosto del 2013

In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.

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Study Pinpoints Cognitive Deficits Due to Cocaine, Finds Potential for Recovery

agosto del 2013

New research demonstrated that, in rhesus monkeys, ongoing cocaine exposure weakens two brain functions that people require for successful behavioral change: cognitive flexibility and memory. But the study determined that these changes may not be permanent.

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Adolescent Cigarette, Alcohol Use Declines as Marijuana Use Rises

febrero del 2013

Fewer teens are using cigarettes, alcohol, and most illicit drugs, according to NIDA’s latest Monitoring the Future study. Troubling  trends persist in marijuana use, however, and nonmedical prescription drug use remains a concern.

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Prenatal Methamphetamine Exposure Linked With Problems

diciembre del 2012

Study findings indicate that children exposed to methamphetamine prenatally show more signs of increased emotionality, anxiety, and depression than nonexposed children at ages 3 and 5 years.

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Animal Research Advances Effort to Develop Vaccines Against Cocaine, Heroin Abuse

septiembre del 2012

New vaccines that aim to promote recovery from cocaine and heroin abuse showed promise in animal testing. Both vaccines induced rats’ immune system to produce high titers of antibodies that inhibit the target drug from reaching the brain. The rats’ behaviors when given access to the target drug indicated that the vaccines reduced the reinforcing effects that, in recovering people, can cause lapses to turn into relapses.

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

abril del 2012

Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

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Stimulant Abusers' Regard for Future Improves With Memory Training

diciembre del 2011

Researchers correlate stimulant abusers’ improved performance on a memory training exerc ise with reductions in delay discounting.

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Marker for Neuronal Damage Resolves a Year after Methamphetamine

diciembre del 2011

New results extend previous findings that some methamphetamine-induced neuronal damage resolves after a year of abstinence.

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