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NIDA Notes Articles: Nicotina

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Resting Brain Studies Shed New Light on Vulnerabilities

noviembre del 2011

Individuals with weak signaling in a nicotine-sensitive brain circuit were more vulnerable to nicotine dependence than those with stronger signaling, according to a study conducted while the subjects’ brains were in a resting state. A second resting-state study finds that the same circuit appears to mediate dependence associated with a genetic risk factor for smoking.

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Nanotechnology Powers Smart Skin Patch

noviembre del 2011

An in vitro test demonstrates the potential of a programmable skin patch that will enable physicians to tailor transdermal medication doses to match patients' fluctuating needs.

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Individual Differences in Decisionmaking Style May Predict Teen Problems

diciembre del 2011

Reports on the relative influence of genes versus environment on adolescents’ choices that involve delayed gratification.

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Financial Strain Hinders Smoking Cessation

diciembre del 2011

Helping smokers deal with financial problems could improve their chances of staying abstinent after receiving treatment, according to a new study. Participants with the most financial strain had the least success in remaining abstinent.

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Program Helps Troubled Boys Reduce Substance Abuse

diciembre del 2011

Chronically delinquent boys in Multidimensional Treatment Foster Care reduced their substance abuse more than boys assigned to Community Group Care.

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In Animals, Receptor Puts Brakes on Nicotine Consumption

Marzo del 2012

New research suggests that differences in tobacco consumption reflect, in part, differences in the functional efficacy of a specific type of receptor in a pathway of the brain. In animal studies, nicotinic acetylcholine receptors with the α5 subunit played a key role in producing aversive responses to nicotine, thereby dissuading further consumption of the drug.

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NIDA Announces Avant-Garde Medication Development Awards

Marzo del 2012
Dr. Thomas Kosten of Baylor College of Medicine and Dr. Peter Burkhard of the University of Connecticut are the recipients of NIDA’s 2011 Avant-Garde Awards for Innovative Medication Development Research. Dr. Kosten is developing a vaccine against methamphetamine abuse and Dr. Burkhard is developing a vaccine to counter nicotine addiction.

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Nicotine Dependence Linked to Higher Rates of Mental Disorders Among Teens

Marzo del 2012
A study of teenagers in Chicago public schools finds higher rates of psychiatric disorders among those with more symptoms of nicotine dependence.

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Desire to Smoke Subsides, But Cigarette Cues Retain Power

abril del 2012

During early abstinence, smokers’ cravings triggered by cigarette cues intensified over time, providing evidence that people can experience a phenomenon previously observed in experiments with animals

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Vouchers Improve Mothers’ Smoking Abstinence and Newborns’ Weight

abril del 2012

Pregnant women who received financial incentives to refrain from smoking during late pregnancy were more successful at remaining abstinent and less likely to have babies with low birth weight, according to data from three trials.

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