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NIDA Notes Articles: Cocaína

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Animal Research Advances Effort to Develop Vaccines Against Cocaine, Heroin Abuse

septiembre del 2012

New vaccines that aim to promote recovery from cocaine and heroin abuse showed promise in animal testing. Both vaccines induced rats’ immune system to produce high titers of antibodies that inhibit the target drug from reaching the brain. The rats’ behaviors when given access to the target drug indicated that the vaccines reduced the reinforcing effects that, in recovering people, can cause lapses to turn into relapses.

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Prenatal Cocaine Exposure Increases Monkeys' Impulsivity Into Adulthood

julio del 2012

Prenatal drug exposure can have behavioral effects that last well into adulthood, according to two studies of adult monkeys prenatally exposed to cocaine. In the first study, drug-exposed monkeys exhibited less flexibility than controls in adjusting to changing circumstances; in the second study, drug-exposed males exhibited a greater preference than controls for having rewards right away, a sign of impulsivity.

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Dr. David Jentsch Receives the 2011 Waletzky Memorial Award

julio del 2012
Dr. J. David Jentsch is the recipient of the 2011 Jacob P. Waletzky Memorial Award for Innovative Research in Drug Addiction and Alcoholism. Dr. Jentsch and colleagues at the University of California, Los Angeles, are studying genetic and neurochemical factors that influence individual differences in inhibitory control.

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Elevated Rates of Drug Abuse Continue for Second Year

junio del 2012
Illicit drug use in the United States in 2010 was at its highest level since 2002, according to the most recent report from the National Survey on Drug Use and Health. A rise in marijuana use drove the increase. A favorable trend of falling cocaine use continued.

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Tobacco Smokers Have High Probability of Transition to Dependence

abril del 2012
First-time smokers have a much higher chance of eventually becoming dependent than first-time users alcohol, cannabis, and cocaine.

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

abril del 2012

Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

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Program Helps Troubled Boys Reduce Substance Abuse

diciembre del 2011

Chronically delinquent boys in Multidimensional Treatment Foster Care reduced their substance abuse more than boys assigned to Community Group Care.

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New Class of Regulators for Addiction Genes

noviembre del 2011
New studies show that microRNAs, snippets of RNA implicated in a wide variety of biological processes, are involved in promoting and inhibiting cocaine addiction. The findings could pave a new path for the development of anti-addiction therapies.

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Disruption of Neuron Production in Adult Rats Increases Cocaine Taking

noviembre del 2011
Drug abuse may diminish production of new neurons in the brain’s hippocampus and thereby increase vulnerability to drug addiction.

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Drugs Contribute to High Rates of Sexually Transmitted Diseases Among Juvenile Offenders

julio del 2011

Describe a study of newly arrested youths where researchers found correlations between the youths' prevalence of these sexually transmitted diseases and their cocaine and marijuana use.

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Toma el reto nacional sobre el coeficiente intelectual (CI) sobre las drogas