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NIDA Notes Articles: Cocaína

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Abstinent Patients Continue to Show Benefits of Treatment

abril del 2007
Reports on data that reviewing the benefits of addiction treatment among abstinent men as compared with those who continued to abuse cocaine.

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Adolescent Cigarette, Alcohol Use Declines as Marijuana Use Rises

febrero del 2013

Fewer teens are using cigarettes, alcohol, and most illicit drugs, according to NIDA’s latest Monitoring the Future study. Troubling  trends persist in marijuana use, however, and nonmedical prescription drug use remains a concern.

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After Release, Jail Inmates’ Substance Use Patterns Relate to Their Choice of Friends

julio del 2013

When the goal is to avoid using alcohol and illicit substances after being released from jail, it’s who one’s friends are that counts most. Self-control is important because it helps a person have the right kind of friends.

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Animal Research Advances Effort to Develop Vaccines Against Cocaine, Heroin Abuse

septiembre del 2012

New vaccines that aim to promote recovery from cocaine and heroin abuse showed promise in animal testing. Both vaccines induced rats’ immune system to produce high titers of antibodies that inhibit the target drug from reaching the brain. The rats’ behaviors when given access to the target drug indicated that the vaccines reduced the reinforcing effects that, in recovering people, can cause lapses to turn into relapses.

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Animation: Building an Anti-Drug Vaccine

diciembre del 2012

The immune system has an extraordinary ability to recognize compounds foreign to the body and eliminate them. NIDA-sponsored scientists are working to harness this ability to create vaccines that will protect individuals against the psychogenic and addictive effects of abused drugs. This animation shows one of the most promising strategies, which has already yielded partial success in producing effective vaccines against nicotine, cocaine, and other drugs.

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Animation: The Rise and Fall of the Cocaine High

noviembre del 2014

This animation shows the rapid passage of cocaine through the brain. It demonstrates that the intensity of the cocaine “high” parallels the trajectory of cocaine levels in the brain.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

diciembre del 2008

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Behavioral Response to Novelty Foreshadows Neurological Response to Cocaine

febrero del 2007
Describes evidence supporting the view that developmental differences in brain systems that use the neurotransmitter dopamine underlie age differences in susceptibility to drug abuse.

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Brain Adaptation May Dampen Effects of Cocaine

octubre del 2010
Reports evidence that a cocaine-induced change in the structure of brain cells represents an adaptive response that may limit the drug’s impact.

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Brain Changes Accompany Cocaine Withdrawal

febrero del 2007
Summarizes an animal study of the neural changes in the amygdala portion of the brain that occur as a result of cocaine exposure followed by withdrawal of the drug.

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