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NIDA Notes Articles: Cocaína

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United States Ranks First in Lifetime Use of Three Drugs

noviembre del 2009

Highlights the disproportionately high rate of Americans who have used cocaine at some time during their lives as compared with other nations surveyed.

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Rare Glutamate Receptor Proliferates After Cocaine Withdrawal

diciembre del 2009

Reports findings that a rare neuroreceptor may be linked to the intensive cravings cocaine abusers experience during their first weeks of abstinence.

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Recovery May Be Harder for Adolescents, Animal Study Suggests

diciembre del 2009

Reports animal study findings that suggest adolescents' heightened sensitivity to drug reward puts them at enhanced risk of addiction and may also increase their challenges in recovery.

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Test Substance Attenuates Signs of Cocaine Withdrawal in Rats

diciembre del 2009

Reports on several drugs that may ward off depression and anxiety, common withdrawal symptoms from cocaine, based on an animal study.

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Peer Interaction Enhances Adolescent Rats' Drug Reward

abril del 2010
Describes an animal study reporting that peer interaction enhances adolescent rats’ drug reward and discusses the impact of these findings to future research on drug reward in social context.

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Stroop Test Identifies Patients at Risk for Treatment Dropout

abril del 2010
Reports on a study of cocaine abusers revealing that the Stroop test may predict which cocaine abusers are likely to drop out of therapy.

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Brain Adaptation May Dampen Effects of Cocaine

octubre del 2010
Reports evidence that a cocaine-induced change in the structure of brain cells represents an adaptive response that may limit the drug’s impact.

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Crack Cocaine Promotes Progression of HIV Infection to AIDS

octubre del 2010
Reports on two studies showing a high prevalence of HIV infection and more rapid progression to disability and death among drug abusers.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

octubre del 2010
Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Brain Opioid Receptor Levels Predict Time to Cocaine Relapse

octubre del 2010
Describes study findings revealing that cocaine abusers who maintain high levels of a certain receptor in their brain during early abstinence relapse sooner than abusers whose levels drop.

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