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NIDA Notes Articles: Cocaína

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

diciembre del 2008

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Brain Proteins Differ in Cocaine-Overdose Victims

diciembre del 2008

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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New Vaccines Are Being Developed Against Addiction and Relapse

diciembre del 2008

Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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Cocaine Locks Rats Into Unrewarding Behaviors

abril del 2009

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction

abril del 2009

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Manic Mice Show Heightened Sensitivity to Rewards

octubre del 2009

Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.

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Combined Treatments Improve Dual Abstinence

octubre del 2009

Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers

octubre del 2009

Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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United States Ranks First in Lifetime Use of Three Drugs

noviembre del 2009

Highlights the disproportionately high rate of Americans who have used cocaine at some time during their lives as compared with other nations surveyed.

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Extended Cocaine Exposure Impairs Cognitive Function in Rats

noviembre del 2009

Reports an animal study presenting evidence that cocaine causes cognitive deficits that can persist well into abstinence.

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Toma el reto nacional sobre el coeficiente intelectual (CI) sobre las drogas