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NIDA Notes Articles: Cocaína

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Impacts of Drugs on Neurotransmission

octubre del 2007

Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.

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Neuropeptide Promotes Drug-Seeking and Craving in Rats

octubre del 2007
Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.

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Cocaine Can Mobilize Stored Dopamine

Marzo del 2008

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Chronic Cocaine Abusers Have Occult Insomnia in Early Abstinence

Marzo del 2008
Reports on research of chronic cocaine abusers who may feel they are sleeping better during early abstinence revealed that the opposite may be true.

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Long-Term Cocaine Abuse Linked With Impaired Heart Function

Marzo del 2008
Summarizes research on the effects of long-term regular cocaine abuse on the cardiovascular system in African Americans.

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Mice With Genetic Alteration Eschew Cocaine

junio del 2008

Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

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Fewer Young Adults Abuse Cocaine and Methamphetamine, National Survey Finds

diciembre del 2008

Reports prevalence rates of illicit drug abuse among youths and young adults based on 2007 data from a national survey of drug use and health.

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Methadone Reduces Rats' Cocaine Seeking

diciembre del 2008

Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

diciembre del 2008

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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Brain Proteins Differ in Cocaine-Overdose Victims

diciembre del 2008

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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Toma el reto nacional sobre el coeficiente intelectual (CI) sobre las drogas