In English
NIDA

NIDA Notes Advanced Search

Specific Drugs

Drug Topics

Temas relacionadas

Do you like these search results?

See all RSS Feeds

Your search for Stimulants returned 43 results. Search again.

Basic Science

Prefrontal Cortex Stimulation Stops Compulsive Drug Seeking in Rats

Researchers have shut down laboratory rats’ compulsive cocaine seeking by stimulating an area of the animals’ prefrontal cortex. The finding raises the possibility that stimulating neurons in this brain area may weaken or break cocaine’s grip on the behavior of people who are addicted to the drug.

Basic Science

Stimulants in “Bath Salts” Produce Effects Similar to MDMA

Mephedrone and methylone, two stimulants commonly found in designer drugs such as “bath salts,” act on the brain much like MDMA (Ecstasy).

Basic Science

Male Rats’ Cocaine Exposure Affects Their Offspring’s Drug Responses

In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.

Basic Science

Study Pinpoints Cognitive Deficits Due to Cocaine, Finds Potential for Recovery

New research demonstrated that, in rhesus monkeys, ongoing cocaine exposure weakens two brain functions that people require for successful behavioral change: cognitive flexibility and memory. But the study determined that these changes may not be permanent.

Epidemiology

Adolescent Cigarette, Alcohol Use Declines as Marijuana Use Rises

Fewer teens are using cigarettes, alcohol, and most illicit drugs, according to NIDA’s latest Monitoring the Future study. Troubling  trends persist in marijuana use, however, and nonmedical prescription drug use remains a concern.

Prevention

Prenatal Methamphetamine Exposure Linked With Problems

Study findings indicate that children exposed to methamphetamine prenatally show more signs of increased emotionality, anxiety, and depression than nonexposed children at ages 3 and 5 years.

Treatment

Animal Research Advances Effort to Develop Vaccines Against Cocaine, Heroin Abuse

New vaccines that aim to promote recovery from cocaine and heroin abuse showed promise in animal testing. Both vaccines induced rats’ immune system to produce high titers of antibodies that inhibit the target drug from reaching the brain. The rats’ behaviors when given access to the target drug indicated that the vaccines reduced the reinforcing effects that, in recovering people, can cause lapses to turn into relapses.

Basic Science

Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

Basic Science

Marker for Neuronal Damage Resolves a Year after Methamphetamine

New results extend previous findings that some methamphetamine-induced neuronal damage resolves after a year of abstinence.

Treatment

Stimulant Abusers' Regard for Future Improves With Memory Training

Researchers correlate stimulant abusers’ improved performance on a memory training exerc ise with reductions in delay discounting.

Basic Science

Disruption of Neuron Production in Adult Rats Increases Cocaine Taking

Drug abuse may diminish production of new neurons in the brain’s hippocampus and thereby increase vulnerability to drug addiction.
Treatment

Medication Reduces Rats' Return to Methamphetamine Seeking

Reports on a new medication strategy under investigated in animal studies that shows promise for preventing relapse to drug abuse.

Prevention

Drugs Contribute to High Rates of Sexually Transmitted Diseases Among Juvenile Offenders

Describe a study of newly arrested youths where researchers found correlations between the youths' prevalence of these sexually transmitted diseases and their cocaine and marijuana use.

Treatment

Methamphetamine Abuse Undermines Dental Health

Describes research that sheds light on the correlation between increased dental disease and methamphetamine abuse.
Basic Science

Cocaine Alters Production of Hundreds of Proteins

Describes research findings that show that chronic cocaine abuse may change the production of many proteins in the neurons of the brain’s reward system, aiding in our understanding how the drug causes addiction.

Treatment

Modafinil Normalizes Sleep During Early Cocaine Abstinence

Describes a study investigating the effectiveness of modafinil in enhancing sleep among cocaine abusers who are currently abstinent.
Treatment

Cocaine Vaccine Helps Some Reduce Drug Abuse

Reports on the results of a clinical trial that tested the effectiveness of a cocaine vaccine designed as a therapy for cocaine abuse and plans underway for a new study of 300 patients to confirm these results.

Treatment

Deep Brain Stimulation Reduces Rats' Cocaine Seeking

Describes results from an animal study involving deep brain stimulation that holds promise as a therapy for severe cocaine addiction.
Basic Science

Brain Adaptation May Dampen Effects of Cocaine

Reports evidence that a cocaine-induced change in the structure of brain cells represents an adaptive response that may limit the drug’s impact.
Basic Science

Brain Opioid Receptor Levels Predict Time to Cocaine Relapse

Describes study findings revealing that cocaine abusers who maintain high levels of a certain receptor in their brain during early abstinence relapse sooner than abusers whose levels drop.
Basic Science

Crack Cocaine Promotes Progression of HIV Infection to AIDS

Reports on two studies showing a high prevalence of HIV infection and more rapid progression to disability and death among drug abusers.
Director's Perspective

New Tools and Strategies to Bolster Behavioral Therapy

Reports on research investigating whether certain medications might strengthen patients' understanding and memory retention.

Treatment

Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.
Treatment

Stroop Test Identifies Patients at Risk for Treatment Dropout

Reports on a study of cocaine abusers revealing that the Stroop test may predict which cocaine abusers are likely to drop out of therapy.
Treatment

Test Substance Attenuates Signs of Cocaine Withdrawal in Rats

Reports on several drugs that may ward off depression and anxiety, common withdrawal symptoms from cocaine, based on an animal study.

Basic Science

Rare Glutamate Receptor Proliferates After Cocaine Withdrawal

Reports findings that a rare neuroreceptor may be linked to the intensive cravings cocaine abusers experience during their first weeks of abstinence.

Treatment

Recovery May Be Harder for Adolescents, Animal Study Suggests

Reports animal study findings that suggest adolescents' heightened sensitivity to drug reward puts them at enhanced risk of addiction and may also increase their challenges in recovery.

Basic Science

Extended Cocaine Exposure Impairs Cognitive Function in Rats

Reports an animal study presenting evidence that cocaine causes cognitive deficits that can persist well into abstinence.

Treatment

Methadone Therapy in Prison Benefits Men a Year Out

Describes clinical trial results providing evidence that methadone maintenance to men in prison can pay off in better retention in community treatment and reduced drug abuse following their release.

Basic Science

Low Dopamine Receptor Availability May Promote Cocaine Addiction

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

Basic Science

Cocaine Locks Rats Into Unrewarding Behaviors

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

Basic Science

Long-Term Cocaine Self-Administration Depresses Brain Activity

Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.

Treatment

Methadone Reduces Rats' Cocaine Seeking

Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

Treatment

Aripiprazole Prevents Rats From Resuming Cocaine Seeking

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

Basic Science

Brain Proteins Differ in Cocaine-Overdose Victims

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

Director's Perspective

New Vaccines Are Being Developed Against Addiction and Relapse

Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

Epidemiology

Fewer Young Adults Abuse Cocaine and Methamphetamine, National Survey Finds

Reports prevalence rates of illicit drug abuse among youths and young adults based on 2007 data from a national survey of drug use and health.

Basic Science

Mice With Genetic Alteration Eschew Cocaine

Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

Basic Science

Cocaine Can Mobilize Stored Dopamine

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

Basic Science

Gene Experiment Confirms a Suspected Cocaine Action

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

Tracing NET

Describes research that has led to the development of a new tool, a new radiotracer, for studying the neurobiology of depression, attention deficit hyperactivity disorder, and stimulant abuse.

Incentives Reduce Stimulant Abuse During Methadone Maintenance

Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

Low-Cost Incentives Improve Outcomes in Stimulant Abuse Treatment

Reports on a study investigating the use of incentives in the form of prizes to motivate outpatients to stay in behavioral therapy and remain drug free.
NIDA Notes

Tags

Drug Topics

Drugs of Abuse

Population Groups

Related Topics

Toma el reto nacional sobre el coeficiente intelectual (CI) sobre las drogas