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One out of every 143 U.S. patients who received a prescription for an opioid painkiller in 2008 obtained prescriptions from multiple physicians in a pattern that suggests misuse or abuse of the drugs.
Almost one-third (32 percent) of the roughly 42,000 Monitoring the Future survey respondents reported having used marijuana during their lifetime. However, abuse of many other drugs—methamphetamine, heroin, cocaine, and some prescription medications—declined.
Researchers found that 1 in 8 high school seniors had used a prescription opioid nonmedically, and 70 percent of these teens had compounded the attendant risk by co-ingesting an opioid with one or more other drugs. Nonmedical opioid use was significantly more prevalent among whites than among African Americans or Hispanics.
A new vaccine hindered the often-abused prescription opioids oxycodone and hydrocodone from entering the brain and suppressed one of the drugs’ signature central nervous system effects. The findings warrant continued development of the vaccine as a potential aid in the treatment of oxycodone and hydrocodone abuse and dependence.
People who use prescription opiates nonmedically are more likely to consider suicide than those who use these medications only appropriately or not at all. A recent NIDA-supported study also disclosed that the risk for suicidal thoughts remains elevated after cessation of use.
Fewer teens are using cigarettes, alcohol, and most illicit drugs, according to NIDA’s latest Monitoring the Future study. Troubling trends persist in marijuana use, however, and nonmedical prescription drug use remains a concern.
NIDA Program Officer Dr. David Thomas speaks about the intertwined problems of pain and prescription opioid abuse, as well as the research supported by NIDA and the National Institutes of Health to address these problems.
Researchers report a significant advance in the search for medications that can suppress pain but avoid opioids’ abuse potential and other undesirable CNS effects. A new compound reduces mouse responses in animal models of neurogenic and chronic inflammatory (e.g., arthritic) pain. The compound, called UB937, enhances the natural pain-killing activity of the neurotransmitter anandamide, and exerts its analgesic effects entirely in peripheral tissues, without entering the brain.
Fewer than 12 percent of adolescents who meet diagnostic criteria for prescription opioid abuse or dependence receive any treatment, according to an analysis of data from the 2005 to 2008 National Survey on Drug Use and Health. The most common reason the adolescents gave for not receiving treatment was their lack of perceived need for it.
Illicit drug use in the United States in 2010 was at its highest level since 2002, according to the most recent report from the National Survey on Drug Use and Health. A rise in marijuana use drove the increase. A favorable trend of falling cocaine use continued.
Reports 2010 rates of marijuana use among 8th, 10th, and 12th grade students, noting that daily use increased by more than 10 percent in all three grades since the 2009 survey. Also reports a rise in ecstasy use.
Reports on 2009 data indicating a rise in drug abuse in the United States and the factors that may have contributed to this increase.
Discusses 2009 prevalence rates of cigarette, alcohol, prescription drug, and illicit drug use among adolescents and discusses trends in use over time.
Highlights trends from a 2008 survey of teenage substance abuse, cigarette smoking and alcohol use and discusses the implications of these changing data.
Describes research to develop new compounds that match or exceed the pain relief provided by opioids while avoiding their shortcomings.
Reports on scientists who pinpointed the biochemical trigger from morphine that sets off a chain reaction that inhibits an immune cell that is key in fighting viruses and cancer.
Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.
Reports on the prevalence of substance abuse among youth based on 2007 data from a national survey of behaviors, attitudes, and values.