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Receptor May Underlie Gender Differences in Response to Smoking Cessation Therapy

Men benefit more than women from nicotine replacement therapy for smoking cessation because nicotine affects a key neuroreceptor differently in the two sexes, a NIDA-sponsored study suggests. The findings highlight the need for alternative therapies for women smokers, and point to the female hormone progesterone as a potential therapeutic target.

Intervention Boosts Treatment Participation, Abstinence Among Depressed Women

Intensive case management was more effective in increasing treatment engagement and reducing alcohol consumption among depressed participants than among those who were not depressed, according to a followup analysis of a substance abuse treatment study involving women on welfare.

Home Visits by Nurses to Low-Income First-Time Mothers Yield Enduring Benefits

A program involving home visits by nurses to low-income first-time mothers, starting during pregnancy and extending into the second year of their children’s lives, has a positive and long-lasting impact on families. Children who participated in the program were less likely than others to report having used alcohol, cigarettes, or marijuana at age 12.

Vouchers Improve Mothers’ Smoking Abstinence and Newborns’ Weight

Pregnant women who received financial incentives to refrain from smoking during late pregnancy were more successful at remaining abstinent and less likely to have babies with low birth weight, according to data from three trials.

Reducing Postpartum Drug Use

Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

Cocaine Locks Rats Into Unrewarding Behaviors

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

James A. Inciardi (1939-2009)

Remembers Dr. James A. Inciardi, founder and co-director of the Center for Drug and Alcohol Studies and professor at the University of Delaware, who died on November 23, 2009.

Intensive Interventions Reduce Risky Sexual Behaviors

Discusses research that compares multiple sessions of motivational and behavioral training with that of a single intervention among male and female substance abusers to reduce high-risk sexual behaviors.

Intervention Improves Abstinence, Employment Among Welfare Recipients

Reports research to study the effectiveness of an intensive case management program to aid female substance abusers who receive welfare in staying off drugs and finding employment.

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