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Receptor May Underlie Gender Differences in Response to Smoking Cessation Therapy

Men benefit more than women from nicotine replacement therapy for smoking cessation because nicotine affects a key neuroreceptor differently in the two sexes, a NIDA-sponsored study suggests. The findings highlight the need for alternative therapies for women smokers, and point to the female hormone progesterone as a potential therapeutic target.

Cocaine Craving Activates Brain Reward Structures; Cocaine "High" Dampens Them

Reports on a study that documenting changing emotional and neurobiological responses to cocaine with successive doses during a single session of drug taking.

Reduced Longevity Among Male Heroin Abusers, 1962-1997

Reviews the changing lifespan of heroin abusers as compared with that of the general U.S. population based on 1962-1997 data.

Cocaine Locks Rats Into Unrewarding Behaviors

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

Intensive Interventions Reduce Risky Sexual Behaviors

Discusses research that compares multiple sessions of motivational and behavioral training with that of a single intervention among male and female substance abusers to reduce high-risk sexual behaviors.

Marijuana Linked With Testicular Cancer

Reports on a study of close to 400 Washington State men that found that those who use marijuana may increase their risk for developing testicular cancer.
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