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Cocaína

Rare Glutamate Receptor Proliferates After Cocaine Withdrawal

Reports findings that a rare neuroreceptor may be linked to the intensive cravings cocaine abusers experience during their first weeks of abstinence.

Brain Opioid Receptor Levels Predict Time to Cocaine Relapse

Describes study findings revealing that cocaine abusers who maintain high levels of a certain receptor in their brain during early abstinence relapse sooner than abusers whose levels drop.

Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

Crack Cocaine Promotes Progression of HIV Infection to AIDS

Reports on two studies showing a high prevalence of HIV infection and more rapid progression to disability and death among drug abusers.

Brain Adaptation May Dampen Effects of Cocaine

Reports evidence that a cocaine-induced change in the structure of brain cells represents an adaptive response that may limit the drug’s impact.

Stroop Test Identifies Patients at Risk for Treatment Dropout

Reports on a study of cocaine abusers revealing that the Stroop test may predict which cocaine abusers are likely to drop out of therapy.

Peer Interaction Enhances Adolescent Rats' Drug Reward

Describes an animal study reporting that peer interaction enhances adolescent rats’ drug reward and discusses the impact of these findings to future research on drug reward in social context.

Brain Mechanism Turns Off Cocaine-Related Memory in Rats

Describes a series of experiments that have added to evidence that a brain enzyme controls key memory processes that link drug experiences, the surroundings in which they take place, and the urge to repeat them.

Modafinil Normalizes Sleep During Early Cocaine Abstinence

Describes a study investigating the effectiveness of modafinil in enhancing sleep among cocaine abusers who are currently abstinent.

Neuropeptide Promotes Behaviors Tied to Addiction and Overeating

Reports on several studies implicating a certain neuropeptide (a signaling molecule) in fostering addition and overeating and discusses implications for addiction treatment.

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