New research suggests that differences in tobacco consumption reflect, in part, differences in the functional efficacy of a specific type of receptor in a pathway of the brain. In animal studies, nicotinic acetylcholine receptors with the α5 subunit played a key role in producing aversive responses to nicotine, thereby dissuading further consumption of the drug.
Dr. Thomas Kosten of Baylor College of Medicine and Dr. Peter Burkhard of the University of Connecticut are the recipients of NIDA’s 2011 Avant-Garde Awards for Innovative Medication Development Research. Dr. Kosten is developing a vaccine against methamphetamine abuse and Dr. Burkhard is developing a vaccine to counter nicotine addiction.
Presents current knowledge on a variety of addiction issues, including nicotine’s affects on brain function; inhalant abuse; genetically-based research and treatment; maternal tobacco use and its effects on children; and a behavior game for young children.
Una de las metas del NIDA es la de ayudar al público a comprender las causas del abuso de drogas y de evitar su comienzo. El abuso de drogas tiene consecuencias serias en nuestros hogares, escuelas y comunidades. Desde la perspectiva del NIDA, el uso de cualquier droga ilícita o el uso inapropiado de las drogas lícitas se considera abuso de drogas.
Describes community systems that monitor the well-being of children and adolescents and lists recommendations that define the next steps for creating and mentoring effective community monitoring systems.