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NIDA

Medication Development

Vaccine May Reduce Fetal Exposure to Nicotine

Describes research on a vaccine developed to facilitate smoking cessation by blocking nicotine penetration into the brain.

Naltrexone-Nicotine Patch Combination Shows Promise

Reports findings from a clinical trial investigating the effectiveness of naltrexone as a supplement to nicotine replacement therapy for smoking cessation.

Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats

Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

Basic Science Discoveries Yield Novel Approaches to Analgesia

Describes research to develop new compounds that match or exceed the pain relief provided by opioids while avoiding their shortcomings.

Lofexidine May Enhance Naltrexone Efficacy

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

Selenium Shows Promise as an Adjunct Therapy for HIV

Reports on a randomized controlled trial of HIV-infected men and women who, as a result of receiving selenium supplements, experienced lower HIV viral load and greater CD4 cell count.

New Vaccines Are Being Developed Against Addiction and Relapse

NIDA Director Nora Volkow

Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

Aripiprazole Prevents Rats From Resuming Cocaine Seeking

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

Combined Treatments Improve Dual Abstinence

Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

Naltrexone via Skin Patch Proves Effectiveness of New Technology

Reports on a new device that creates tiny painless punctures in the skin to allow medication to flow evenly from a skin patch into dermal capillaries and the bloodstream.

Páginas

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