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Consecuencias médicas

HIV Infection Accelerates Hepatitis C–Related Liver Fibrosis

Study patients with HIV­­–hepatitis C coinfection progressed to successive degrees of severity of liver fibrosis 9 years sooner than those infected with HCV alone. Further findings from the study suggest that suppressing HIV with antiretroviral medications may slow HCV-related liver fibrosis.

Medications That Treat Opioid Addiction Do Not Impair Liver Health

A trial of buprenorphine/naloxone (Bup/Nx) showed no evidence that the medicine was associated with liver damage. The drug gave results similar to those of methadone. The study data indicate that although most patients can be treated safely with either methadone or Bup/Nx without major concern for liver injury, clinicians are advised to continue to monitor the liver health of their patients who are on methadone or Bup/Nx therapy.

Prenatal Methamphetamine Exposure Linked With Problems

Study findings indicate that children exposed to methamphetamine prenatally show more signs of increased emotionality, anxiety, and depression than nonexposed children at ages 3 and 5 years.

Potential Pain Medication Targets Peripheral Nerves

Researchers report a significant advance in the search for medications that can suppress pain but avoid opioids’ abuse potential and other undesirable CNS effects. A new compound reduces mouse responses in animal models of neurogenic and chronic inflammatory (e.g., arthritic) pain. The compound, called UB937, enhances the natural pain-killing activity of the neurotransmitter anandamide, and exerts its analgesic effects entirely in peripheral tissues, without entering the brain.

Prenatal Cocaine Exposure Increases Monkeys' Impulsivity Into Adulthood

Prenatal drug exposure can have behavioral effects that last well into adulthood, according to two studies of adult monkeys prenatally exposed to cocaine. In the first study, drug-exposed monkeys exhibited less flexibility than controls in adjusting to changing circumstances; in the second study, drug-exposed males exhibited a greater preference than controls for having rewards right away, a sign of impulsivity.

Research Focuses on Groups With High Smoking Rates

NIDA Director Nora Volkow
Dr. Volkow discusses NIDA’s efforts to develop effective antismoking treatments for populations with persistently high rates of smoking, such as people with psychiatric disorders, high school dropouts, and Native Americans.

NIDA creates easy-to-read website on drug abuse

A new, easy-to-read website on drug abuse designed for adults with a low reading literacy level (eighth grade or below) was launched today by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.  The si


Marker for Neuronal Damage Resolves a Year after Methamphetamine

New results extend previous findings that some methamphetamine-induced neuronal damage resolves after a year of abstinence.

Substance Abuse Among Older Adults

NIDA Director Nora Volkow

Understanding and responding to drug abuse among America’s aging population becomes more urgent as a growing percentage of baby boomers enter the over-50 age bracket.

Letter from the Director

The abuse of methamphetamine—a potent and highly addictive stimulant—remains an extremely serious problem in the United States. According to data from the 2012 National Survey on Drug Use and Health (NSDUH), over 12 million people (4.7 percent of the population) have tried methamphetamine at least once. NSDUH also reports that approximately 1.2 million people used methamphetamine in the year leading up to the survey.

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