Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.
Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.
Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.
Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.
Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.
Describes a booklet that explains what scientists know about how drug addiction changes the brain and affects behavior and clears up misconceptions about drug addiction.
Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.
Describes a knowledge- and resource-sharing system for NIH-funded neuroscientists to access to data, advanced research tools, and technical assistance.
Reports on evidence that toluene abuse can harm the nervous system and body, although scientists know relatively little about its specific actions.