Describes the role of the Division of Clinical Neuroscience and Behavioral Research in NIDA’s drug abuse and addiction research plan.
Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.
Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.
Describes an NIH-wide obesity task force and research plan and explores some of the links between addiction and compulsive eating.
Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.
Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.
Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.