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NIDA

Investigadores

Sertraline Does Not Help Methamphetamine Abusers Quit

Describes a new research finding indicating that the antidepressant sertraline (Zoloft), prescribed to relieve depression during the methamphetamine withdrawal process, may make quitting harder.

Researchers Develop a New Tracer for Cannabinoid Receptor

Describes a new chemical tracer that binds specifically to cannabinoid receptors making it potentially useful in future research to clarify the relationship between the receptors and drug abuse.

Cocaine Can Mobilize Stored Dopamine

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

Bupropion Reduces Meth's Subjective Effects and Cue-Induced Craving

Describes a study investigating the use of the antidepressant bupropion as a potential therapy for methamphetamine addiction.

Long-Term Cocaine Abuse Linked With Impaired Heart Function

Summarizes research on the effects of long-term regular cocaine abuse on the cardiovascular system in African Americans.

HIV Patients Show Better Immune Recovery With Early Initiation of HAART

Presents evidence that among men and women with HIV, those who received early initiation of HAART therapy, those with higher CD4+ levels, achieved better immune recovery.

Not All Mesolimbic Dopamine Neurons Are Alike

Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.

Epigenetics: The Promise of a New Science

NIDA Director Nora Volkow

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

Combination Treatment Extends Marijuana Abstinence

Describes research investigating the use of a treatment that combines vouchers and cognitive behavioral therapy as compared with the use of either treatment alone for marijuana abuse.

Chronic Cocaine Abusers Have Occult Insomnia in Early Abstinence

Reports on research of chronic cocaine abusers who may feel they are sleeping better during early abstinence revealed that the opposite may be true.

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