Investigadores

Describes investigations to advance the development of potential drug abuse relapse prevention agents by targeting specific receptors of the neurochemical serotonin.

Summarizes animal studies indicating that an antipsychotic drug, trifluoperazine, prevents morphine tolerance in mice.

Reports on research that successfully traced rats’ liking for sweets to a 1-cubic millimeter site in the medial shell of the nucleus accumbens in the brain.

Reports findings from a clinical trial investigating the effectiveness of naltrexone as a supplement to nicotine replacement therapy for smoking cessation.

Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

Reports on data that reviewing the benefits of addiction treatment among abstinent men as compared with those who continued to abuse cocaine.

Reports on a study to investigate the use of methadone maintenance for heroin addicts wait-listed for a treatment program to encourage their likelihood to enroll in the program.

Reports on the research underway to identify gene variations associated with nicotine addiction and the interaction of genetic makeup, experiences, and surroundings to addiction.

Presents results of a pilot study to investigate the safety and efficacy of a new long-lasting injectable formulation of naltrexone to treat of heroin addiction in an outpatient setting.

Announces the recipient of a 2006 award for innovation in research on drug addiction and alcoholism, Dr. Yavin Shaham, and describes his research which focused on the stress-induced drug use relapse.