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Prescription Drugs

What is Prescription Drug Abuse:

Some medications have psychoactive (mind-altering) properties and, because of that, are sometimes abused—that is, taken for reasons or in ways or amounts not intended by a doctor, or taken by someone other than the person for whom they are prescribed. In fact, prescription and over-the-counter (OTC) drugs are, after marijuana (and alcohol), the most commonly abused substances by Americans 14 and older. Learn more

Commonly Abused Drugs:

Commonly abused classes of prescription drugs include opioids (for pain), central nervous system (CNS) depressants (for anxiety and sleep disorders), and stimulants (for ADHD and narcolepsy).

Opioids include:

  • Fentanyl (Duragesic®)
  • Hydrocodone (Vicodin®)
  • Oxycodone (OxyContin®)
  • Oxymorphone (Opana®)
  • Propoxyphene (Darvon®)
  • Hydromorphone (Dilaudid®)
  • Meperidine (Demerol®)
  • Diphenoxylate (Lomotil®)

Central nervous system depressants include:

  • Pentobarbital sodium (Nembutal®)
  • Diazepam (Valium®)
  • Alprazolam (Xanax®)

Stimulants include:

  • Dextroamphetamine (Dexedrine®)
  • Methylphenidate (Ritalin® and Concerta®)
  • Amphetamines (Adderall®)

Statistics and Trends

2012 Monitoring the Future (MTF) Study: for 8th-Graders, 10th-Graders, and 12th-Graders (in percent)*
Drug Time
Period
8th-
Graders
10th-
Graders
12th-
Graders
Narcotics other than Heroin Lifetime - - 12.2
Past Year - - 7.9
Past Month - - [3.0]
Amphetamine Lifetime 4.5 8.9 12.0
Past Year 2.9 6.5 7.9
Past Month 1.3 2.8 3.3

* Data in brackets indicate statistically significant change from the previous year.

 

National Survey of Drug Use and Health
for Ages 12 and Older

2008-2011 (in percent)*
Drug Time
Period
Ages 12 or
Older
Ages
12-17
Ages
18-25
Ages 26
or Older
Psychotherapeutics
(Nonmedical Use)
Lifetime 19.9 10.1 [27.3] 19.8
Past Year [5.7] 7.0 [12.7] 4.3
Past Month [2.4] 2.8 [5.0] 1.9

* Data in brackets indicate statistically significant change from the previous year.

 

Related Videos

Featured Publications

Prescription and Over-the-Counter Medications (DrugFacts)

Published June 2009. Revised May 2013.
Provides an overview of commonly abused prescription drugs—opioids, central nervous system depressants, and stimulants—and explains how they affect the brain, treatments available, and reported use. En Español

High School and Youth Trends (DrugFacts)

Revised December 2012.
Describes trends in high school and youth drug abuse and addiction, with an emphasis on marijuana, cigarettes, prescription drugs, alcohol and ecstasy. En Español

Nationwide Trends (DrugFacts)

Published April 2011. Revised December 2012.
Examines nationwide trends in drug abuse and addiction among youth, describing lifetime, past year and past month use for alcohol, tobacco, illicit drugs, and prescription drugs. En Español

Publication Cover

Principles of Drug Addiction Treatment: A Research-Based Guide (Third Edition)

Published October 1999. Revised December 2012.
Presents research-based principles of addiction treatment for a variety of drugs, including nicotine, alcohol, and illicit and prescription drugs, that can inform drug treatment programs and services. En Español

After Cannabis, Nonmedical use of the Prescriptions and Over-the-Counter Medications Account for Most of the Commonly Abused Drugs in 12th Graders (in the past year)

Prescription Drug Abuse (Topics in Brief)

Revised December 2011.
Provides a brief overview of the non-medical use of prescription drugs, examining prevalence, health risks associated with use, treatment options, and research underway on the topic.

Related Resources

Other Resources

Past information on many drugs of abuse is available on our Archives site.

This page was last updated December 2012

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Looking for Treatment?

Use the SAMHSA Treatment Locator or 1-800-662-HELP.

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Research Report

Research Report Cover

Prescription Drugs: Abuse and Addiction

Examines the non-medical use of prescription drugs-opioids, central nervous system depressants, and stimulants-describing adverse health effects of their use and the prevention and treatment of addiction.

Safe Disposal of Medicines

Opioid and Pain Management CME courses link
eNIDA. eTool Innovations for Provider Education. Drug Screening Tool

Featured Publication

Featured Publication

Drugs, Brains, and Behavior - The Science of Addiction

As a result of scientific research, we know that addiction is a disease that affects both brain and behavior.

Easy-to-read Drug Facts

Prescription Drug Abuse

Medicine Abuse Project - Drugfee.org
Learn what you can do to
prevent medicine abuse at
medicineabuseproject.org