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Topics in Brief

Medication-Assisted Treatment for Opioid Addiction

Opioids act on specific receptors in the brain and the body, which also interact with naturally produced substances known as endorphins or enkephalins – important in regulating pain. While prescription pain relievers can be highly beneficial if used as prescribed, opioids as a general class of drugs have a high potential for abuse.

Substance Abuse among the Military, Veterans, and their Families

Scope of the problem

The ongoing operations in Iraq (Operation Iraqi Freedom) and Afghanistan (Operation Enduring Freedom) continue to strain military personnel, returning veterans, and their families. Some have experienced long and multiple deployments, combat exposure, and physical injuries, as well as post-traumatic stress disorder (PTSD) and traumatic brain injury (TBI).

Tobacco and Nicotine Research

Tobacco use is the leading preventable cause of disease, disability, and death in the United States. Cigarette smoking results in more than 400,000 preventable deaths each year – about one in every five U.S. deaths. Despite the well-documented health costs of smoking, many smokers have great difficulty quitting, and many others are still becoming addicted – about 1200 per day in the U.S. Researchers are striving to understand the numerous effects of nicotine on the brain and body, determine why it is so addictive, and help smokers break its hold for good.

Tobacco Addiction

According to the Centers for Disease Control and Prevention, there has been a 50 percent decline in the number of smokers since 1965.

Percent of Students Reporting Daily  Cigarette Use, by Grade

Drugs, Brains, and Behavior: The Science of Addiction

Science of Addiction coverMany people today do not understand why individuals become addicted to drugs, or how drugs change the brain to foster compulsive drug abuse. This new NIDA booklet aims to fill that knowledge gap by providing scientific information about the disease of drug addiction, including the many harmful consequences and basic approaches to prevent and treat the disease. View the Science of Addiction Booklet.

Drug Abuse Prevention

Drug abuse is preventable.

Understanding the Problem

Each year, drug abuse and addiction cost taxpayers nearly $534 billion in preventable health care, law enforcement, crime, and other costs. For NIDA, the key word in this assessment is "preventable." The best approach to reducing the tremendous toll substance abuse exacts from individuals, families, and communities is to prevent the damage before it occurs.

Prescription Drug Abuse

Prescription drug abuse is the intentional use of a medication without a prescription; in a way other than as prescribed; or for the experience or feeling it causes. It is not a new problem, but one that deserves renewed attention. For although prescription drugs can be powerful allies, they also pose serious health risks related to their abuse.

Prenatal Exposure to Drugs of Abuse

Drug Abuse among Pregnant Women in the U.S.

Exposure to substances of abuse can affect individuals across the lifespan, starting in utero. While most pregnant women do not abuse illicit drugs, combined 2008 and 2009 data from the National Survey on Drug Use and Health found that among pregnant women ages 15 to 44, the youngest ones generally reported the greatest substance use. Also, pregnant women ages 15 to 17 had similar rates of illicit drug use (15.8 percent or 14,000 women) as women of the same age who were not pregnant (13.0 percent or 832,000 women).

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