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NIDA

Pregnant Women

Prenatal Methamphetamine Exposure Linked With Problems

Study findings indicate that children exposed to methamphetamine prenatally show more signs of increased emotionality, anxiety, and depression than nonexposed children at ages 3 and 5 years.

Buprenorphine During Pregnancy Reduces Neonate Distress

Sublingual buprenorphine is a safe and effective alternative to methadone for treating opioid dependence during pregnancy, finds the Maternal Opioid Treatment: Human Experimental Research (MOTHER) study, a NIDA-supported clinical trial. Women who received either medication had similar pregnancy and birth outcomes, but infants born to women who received buprenorphine had milder symptoms of neonatal opioid withdrawal.

Home Visits by Nurses to Low-Income First-Time Mothers Yield Enduring Benefits

A program involving home visits by nurses to low-income first-time mothers, starting during pregnancy and extending into the second year of their children’s lives, has a positive and long-lasting impact on families. Children who participated in the program were less likely than others to report having used alcohol, cigarettes, or marijuana at age 12.

Women and Sex/Gender Differences Research Program

NIDA’s Women and Sex/Gender Differences Research Program focuses on gender-specific addiction risk factors and treatment needs.

Research Focuses on Groups With High Smoking Rates

NIDA Director Nora Volkow
Dr. Volkow discusses NIDA’s efforts to develop effective antismoking treatments for populations with persistently high rates of smoking, such as people with psychiatric disorders, high school dropouts, and Native Americans.

Vouchers Improve Mothers’ Smoking Abstinence and Newborns’ Weight

Pregnant women who received financial incentives to refrain from smoking during late pregnancy were more successful at remaining abstinent and less likely to have babies with low birth weight, according to data from three trials.

Nicotine Alters the Developing Rat Brain

Describes animal studies that suggested exposure to the drug during gestation or adolescence may cause lasting alterations in reward and motivation circuits.

Vaccine May Reduce Fetal Exposure to Nicotine

Describes research on a vaccine developed to facilitate smoking cessation by blocking nicotine penetration into the brain.

Methamphetamine Restricts Fetal Growth, Increases Lethargy in Newborns

Reports on research showing that newborns whose mothers abused methamphetamine during pregnancy showed lower rates of fetal growth as compared with unexposed newborns.

Behavioral Problems Related to Maternal Smoking During Pregnancy Manifest Early in Childhood

Describes research providing evidence that maternal smoking during pregnancy contributes to behavioral conduct disorders among toddlers, school-age children, and teens.

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