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NIDA

Stimulants

Modafinil Normalizes Sleep During Early Cocaine Abstinence

Describes a study investigating the effectiveness of modafinil in enhancing sleep among cocaine abusers who are currently abstinent.

Deep Brain Stimulation Reduces Rats' Cocaine Seeking

Describes results from an animal study involving deep brain stimulation that holds promise as a therapy for severe cocaine addiction.

Cocaine Alters Production of Hundreds of Proteins

Describes research findings that show that chronic cocaine abuse may change the production of many proteins in the neurons of the brain’s reward system, aiding in our understanding how the drug causes addiction.

Cocaine Vaccine Helps Some Reduce Drug Abuse

Reports on the results of a clinical trial that tested the effectiveness of a cocaine vaccine designed as a therapy for cocaine abuse and plans underway for a new study of 300 patients to confirm these results.

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