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Opioids

Patient-Centered Learning: Substance Abuse in a Physician - The Connor Johnson Case

Summary

Highlights substance abuse among physicians and offers a case study to help students understand the risks and signs of drug abuse in the physician population.

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Prescription Drug Abuse: An Introduction

Summary

Provides an overview of prescription drug abuse, framed within the clinical scenario of chronic pain management in the outpatient setting.

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Opioid Risk Management Objective Structured Clinical Exams (OSCE)

Summary

Uses performance-based assessments to examine approaches to managing patients who require long term opioid analgesics for chronic pain.

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Antipsychotic Drug Prevents Morphine Tolerance in Mice

Summarizes animal studies indicating that an antipsychotic drug, trifluoperazine, prevents morphine tolerance in mice.

Scientists Pinpoint Brain's Sweet Tooth

Reports on research that successfully traced rats’ liking for sweets to a 1-cubic millimeter site in the medial shell of the nucleus accumbens in the brain.

Meeting Reviews Progress On Prescription Opioid Misuse

Describes a meeting of researchers and clinicians who gathered to discuss the challenges in balancing appropriate pain treatment with efforts to minimize prescription opioid misuse.

Not All Mesolimbic Dopamine Neurons Are Alike

Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.

Chromosome 17 Harbors Opioid Dependence Genes

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

Reduced Longevity Among Male Heroin Abusers, 1962-1997

Reviews the changing lifespan of heroin abusers as compared with that of the general U.S. population based on 1962-1997 data.

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