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NIDA

Heroin

Animal Research Advances Effort to Develop Vaccines Against Cocaine, Heroin Abuse

New vaccines that aim to promote recovery from cocaine and heroin abuse showed promise in animal testing. Both vaccines induced rats’ immune system to produce high titers of antibodies that inhibit the target drug from reaching the brain. The rats’ behaviors when given access to the target drug indicated that the vaccines reduced the reinforcing effects that, in recovering people, can cause lapses to turn into relapses.

More Convenient Preparations of Buprenorphine Pass Test

Soluble-film preparations of buprenorphine suppressed heroin abusers’ withdrawal symptoms with no serious side effects in a recent clinical trial. They dissolved more rapidly in the mouth than the pill form of the medication, providing faster relief.

Buprenorphine During Pregnancy Reduces Neonate Distress

Sublingual buprenorphine is a safe and effective alternative to methadone for treating opioid dependence during pregnancy, finds the Maternal Opioid Treatment: Human Experimental Research (MOTHER) study, a NIDA-supported clinical trial. Women who received either medication had similar pregnancy and birth outcomes, but infants born to women who received buprenorphine had milder symptoms of neonatal opioid withdrawal.

Study provides clues for designing new anti-addiction medications

Scientists are now one step closer to developing anti-addiction medications, thanks to new research that provides a better understanding of the properties of the only member of the opioid receptor family whose activation counteracts the rewarding effects of addictive drugs.


NIDA creates easy-to-read website on drug abuse

A new, easy-to-read website on drug abuse designed for adults with a low reading literacy level (eighth grade or below) was launched today by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.  The si


Program Helps Troubled Boys Reduce Substance Abuse

Chronically delinquent boys in Multidimensional Treatment Foster Care reduced their substance abuse more than boys assigned to Community Group Care.

Painkiller Abuse Treated by Sustained Buprenorphine/Naloxone

People addicted to prescription painkillers reduce their opioid abuse when given sustained treatment with the medication buprenorphine plus naloxone (Suboxone), according to research published in yesterday's Archives of General Psychiatry and conducted by the National Institute on Drug Abuse (NID


Opioids

Describes to young teens how opioids, such as Vicodin, morphine, heroin, and codeine, affect the brain—including the limbic system—and the nervous system.

Published: January 1997
Revised: September 2014


Read this publication online at the NIDA for Teens Web site »

Interim Methadone Raises Odds of Enrolling in Comprehensive Treatment

Reports on a study to investigate the use of methadone maintenance for heroin addicts wait-listed for a treatment program to encourage their likelihood to enroll in the program.

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