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NIDA

Stress

Stress-Induced Enzyme Compounds Methamphetamine Neurotoxicity

Ketoprofen, an anti-inflammatory agent commonly prescribed to treat arthritis, reduces neuronal damage in rats that have been exposed to chronic stress and methamphetamine. If this finding of a recent NIDA-supported study extrapolates to humans, anti-inflammatory medications may gain a place in the treatment of methamphetamine addiction.

Staff Stress Affects Patients’ Engagement in Therapy

Several factors contribute to treatment professionals’ stress and burnout, including how much influence they feel they have in their organization and their caseload. Surprisingly, a NIDA-supported study found that the link between staff stress and burnout was weaker in programs with higher patient caseloads than those with lower caseloads. In addition, program administrators can help counselors reduce their stress by giving them a voice in organizational policies and procedures.  

High Rates of Job Leaving Among Addiction Counselors

Substance abuse counselors and clinical supervisors disclosed high job turnover rates in a survey of 27 treatment organizations.

Medication Reduces Rats' Return to Methamphetamine Seeking

Reports on a new medication strategy under investigated in animal studies that shows promise for preventing relapse to drug abuse.

Treatment Dropout Linked With Elevated Stress Response

Summarizes a study to determine whether a stress-related biological marker in saliva can predict how long a drug user will remain in treatment.

Stress Response May Underlie African- Americans' Reduced Pain Tolerance

Summarizes research suggesting a physiological difference as the explanation for African-Americans' reported low tolerance for pain.

Studies Focus on Acculturation and Hispanic Youth

Summarizes a study that analyzes factors associated with the risk of drug addiction among 19- to 21-year-old Hispanic women born in the United States as compared with immigrants.

Lofexidine May Enhance Naltrexone Efficacy

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

Substance Abuse Among Troops, Veterans, and Their Families

NIDA Director Nora Volkow

Highlights the need for research to assess and find solutions to a potential rise in substance abuse among service men and women, veterans, and their families.

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