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NIDA

Addiction Science

Long-Term Cocaine Abuse Linked With Impaired Heart Function

Summarizes research on the effects of long-term regular cocaine abuse on the cardiovascular system in African Americans.

Not All Mesolimbic Dopamine Neurons Are Alike

Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.

Epigenetics: The Promise of a New Science

NIDA Director Nora Volkow

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

Chromosome 17 Harbors Opioid Dependence Genes

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

Alcohol Abuse Makes Prescription Drug Abuse More Likely

Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.

Booklet Explains the Science of Addiction

Describes a booklet that explains what scientists know about how drug addiction changes the brain and affects behavior and clears up misconceptions about drug addiction.

Mice With Genetic Alteration Eschew Cocaine

Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

Neuroscience Blueprint Promotes Efficiency, Synergy

NIDA Director Nora Volkow

Describes a knowledge- and resource-sharing system for NIH-funded neuroscientists to access to data, advanced research tools, and technical assistance.

Animal Studies Elaborate Toluene's Effects

Reports on evidence that toluene abuse can harm the nervous system and body, although scientists know relatively little about its specific actions.

New Technique Links 89 Genes to Drug Dependence

Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.

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