New research suggests that differences in tobacco consumption reflect, in part, differences in the functional efficacy of a specific type of receptor in a pathway of the brain. In animal studies, nicotinic acetylcholine receptors with the α5 subunit played a key role in producing aversive responses to nicotine, thereby dissuading further consumption of the drug.
In a new series of studies tracing the molecular events that occur in the brain as memories are formed and preserved, researchers find that certain epigenetic changes may promote vulnerability to relapse.
Presents current knowledge on a variety of addiction issues, including nicotine’s effects on brain function, inhalant abuse, and maternal tobacco use and its effects on children. Also discusses genetically based research and treatment and a classroom behavior management method called the "Good Behavior Game."
Features recent research on drug abuse and criminal justice, including interventions to promote successful re-entry, nutrition issues for HIV-infected drug abusers, and recovery-oriented systems of care.
Reports on the cognitive effects of addiction, potential genetic influences, strategies for training counselors, cost evaluation of evidence-based treatments, and a trial underway on brief strategic family therapy.