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Addiction Science

Well-Known Mechanism Underlies Benzodiazepines' Addictive Properties

New research establishes that benzodiazepines cause addiction in a way similar to that of opioids, cannabinoids, and the club drug GHB. The discovery opens the door to designing new benzodiazepines that counteract anxiety but are not addictive.

Women and Sex/Gender Differences Research Program

NIDA’s Women and Sex/Gender Differences Research Program focuses on gender-specific addiction risk factors and treatment needs.

Blending conference translates substance abuse research into practice

Experts will share the latest clinical research with addiction treatment professionals, healthcare providers, policy makers, and others during the April 19th Blending Conference in Atlanta, Georgia.


Study provides clues for designing new anti-addiction medications

Scientists are now one step closer to developing anti-addiction medications, thanks to new research that provides a better understanding of the properties of the only member of the opioid receptor family whose activation counteracts the rewarding effects of addictive drugs.


New Method Uncovers How Internal States Influence the Living Brain to Change Behavior

In an innovative NIDA-funded study, published in Cell, scientists introduced a modified dopamine receptor gene into the brain of a living vinegar fly

In Animals, Receptor Puts Brakes on Nicotine Consumption

New research suggests that differences in tobacco consumption reflect, in part, differences in the functional efficacy of a specific type of receptor in a pathway of the brain. In animal studies, nicotinic acetylcholine receptors with the α5 subunit played a key role in producing aversive responses to nicotine, thereby dissuading further consumption of the drug.

Stimulant Abusers' Regard for Future Improves With Memory Training

Researchers correlate stimulant abusers’ improved performance on a memory training exerc ise with reductions in delay discounting.

NIDA's Drug Abuse Research Advances Science as a Whole

NIDA Director Nora Volkow

NIDA Director Dr. Nora D. Volkow summarizes instances where discoveries with broad implications for human health arose from scientists seeking answers to addiction problems.

Molecular Alterations of DNA Contribute to Persistence of Memory

In a new series of studies tracing the molecular events that occur in the brain as memories are formed and preserved, researchers find that certain epigenetic changes may promote vulnerability to relapse.

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