En español
NIDA

Addiction Science

Talking to the Dalai Lama about Addiction Science

Recently, I had the privilege of visiting Dharamsala, India, for a dialogue with His Holiness the Dalai Lama about addiction science, as part of a five-day conference at his Mind and Life Institute. I was very impressed at the Tibetan Buddhist leader’s personal interest in the brain, and in his desire to convene a small group of scientists from around the world along with Buddhist contemplatives and other scholars to discuss the topic of craving, desire, and addiction.

Dr. Marilyn Huestis Q & A: Matching Drug Effects to Drug Concentrations

Dr. Marilyn Huestis of NIDA’s Intramural Research Program talks about conducting research on drug effects with human subjects, developing tests to help law enforcement identify drugged drivers, and an assay to help identify children whose prenatal exposure to anti-HIV drugs may put them at risk for adverse developmental outcomes.

Stimulants in “Bath Salts” Produce Effects Similar to MDMA

Mephedrone and methylone, two stimulants commonly found in designer drugs such as “bath salts,” act on the brain much like MDMA (Ecstasy).

Study Pinpoints Cognitive Deficits Due to Cocaine, Finds Potential for Recovery

New research demonstrated that, in rhesus monkeys, ongoing cocaine exposure weakens two brain functions that people require for successful behavioral change: cognitive flexibility and memory. But the study determined that these changes may not be permanent.

Advancing Psychiatric Practice through the Science of Addiction

The National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health, will present a special research track at the American Psychiatric Association’s (APA’s) 166th annual meeting in San Francisco from May 18 to 22.


NIH study sheds light on how to reset the addicted brain

Could drug addiction treatment of the future be as simple as an on/off switch in the brain?


N-Acetylcysteine Postsynaptic Effect Limits Efficacy

Clinical trials of N-acetylcysteine to help people recovering from drug abuse avoid relapse have demonstrated only moderate efficacy. New NIDA-supported research shows that while a low dose of the medication activates receptors associated with lowered drug-seeking behavior, a higher dose appears to activate receptors associated with increased drug-seeking behavior. The result suggests that a medication or combination of medications that stimulate the receptor GluR2/3 and block mGluR5 may work better than N-acetylcysteine alone.

Animation: Building an Anti-Drug Vaccine

The immune system has an extraordinary ability to recognize compounds foreign to the body and eliminate them. NIDA-sponsored scientists are working to harness this ability to create vaccines that will protect individuals against the psychogenic and addictive effects of abused drugs. This animation shows one of the most promising strategies, which has already yielded partial success in producing effective vaccines against nicotine, cocaine, and other drugs.

Dr. David Jentsch Receives the 2011 Waletzky Memorial Award

Dr. J. David Jentsch is the recipient of the 2011 Jacob P. Waletzky Memorial Award for Innovative Research in Drug Addiction and Alcoholism. Dr. Jentsch and colleagues at the University of California, Los Angeles, are studying genetic and neurochemical factors that influence individual differences in inhibitory control.

Investigators Map Functional Networks in the Rat Brain

Researchers have mapped the fundamental functional organization of the rat brain and shown that it resembles that of the human brain.

Pages

Subscribe to Addiction Science