En español
NIDA

Basic Science

Gene Experiment Confirms a Suspected Cocaine Action

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

Cocaine Can Mobilize Stored Dopamine

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

Not All Mesolimbic Dopamine Neurons Are Alike

Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.

Chromosome 17 Harbors Opioid Dependence Genes

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

Methamphetamine Restricts Fetal Growth, Increases Lethargy in Newborns

Reports on research showing that newborns whose mothers abused methamphetamine during pregnancy showed lower rates of fetal growth as compared with unexposed newborns.

Morphine-Induced Immunosuppression, From Brain to Spleen

Reports on scientists who pinpointed the biochemical trigger from morphine that sets off a chain reaction that inhibits an immune cell that is key in fighting viruses and cancer.

Mice With Genetic Alteration Eschew Cocaine

Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

Animal Studies Elaborate Toluene's Effects

Reports on evidence that toluene abuse can harm the nervous system and body, although scientists know relatively little about its specific actions.

New Technique Links 89 Genes to Drug Dependence

Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.

Optical Technologies Expand Vistas Into the Brain

Describes new tools under development, including one to visualize cells deep in the brain and another one that remotely activates brain cells.

Pages

Subscribe to Basic Science