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Brain Changes Accompany Cocaine Withdrawal

Summarizes an animal study of the neural changes in the amygdala portion of the brain that occur as a result of cocaine exposure followed by withdrawal of the drug.

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Medical Care During Addiction Treatment Reduces Hospital Use

Reports on an analysis comparing three types of addiction treatment programs: methadone maintenance programs, long-term residential programs, and nonmethadone programs.

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Studies Focus on Acculturation and Hispanic Youth

Summarizes a study that analyzes factors associated with the risk of drug addiction among 19- to 21-year-old Hispanic women born in the United States as compared with immigrants.

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GHB Intoxication Reports Decline in California

Highlights statistics on the number of reports of gamma-hydroxybutyrate (GHB) use intoxication in California from 1999 to 2003.

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How Drug Abuse Affects the Brain and Alters Behavior Are Key Questions Driving Division's Work

Discusses the work of NIDA’s Division of Basic Neuroscience and Behavioral Research, the Institute’s locus for studies into the fundamental brain mechanisms underlying drug abuse and addiction.

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Nicotine Alters the Developing Rat Brain

Describes animal studies that suggested exposure to the drug during gestation or adolescence may cause lasting alterations in reward and motivation circuits.

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Cocaine Craving Activates Brain Reward Structures; Cocaine "High" Dampens Them

Reports on a study that documenting changing emotional and neurobiological responses to cocaine with successive doses during a single session of drug taking.

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Cocaine Abusers' Pretreatment Cue Responses Predict Recovery Success

Reports on the work of researchers who used brain images to correlate cocaine-addicted patients' regional brain responses to drug cues with their outcomes in subsequent treatment.

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Behavioral Response to Novelty Foreshadows Neurological Response to Cocaine

Describes evidence supporting the view that developmental differences in brain systems that use the neurotransmitter dopamine underlie age differences in susceptibility to drug abuse.

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Journal Highlights Opportunities in Hispanic Drug Abuse Research

Reviews a journal supplement that compiles information on drug abuse research in the Hispanic population.

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