This study was undertaken to compare, in an outpatient setting, the relative advantage of two Suboxone® (Bup/Nx) tapering schedules (one rapid and one gradual) following four weeks of Suboxone® stabilization, as reflected by the proportion of participants providing opiate free urines at the end of the taper regimen. In total, 516 participants were randomized to one of two taper schedules, either 7 days or 28 days. The reason for conducting this study was not to advocate for short-term treatment, but to determine the relative ease of using a more rapid vs. a gradual taper should someone need to discontinue Bup/Nx.
Ling, W., et al. (2009). Buprenorphine tapering schedule and illicit opioid use. Addiction 104: 256-265.
Participating Nodes and Community Treatment Programs
Pacific Region Node (Lead Node)
Long Island Regional Node (Inactive)
New England Node (Inactive)
Oregon-Hawaii Node (Inactive)
Rocky Mountain Regional Node (Inactive)
As a result of scientific research, we know that addiction is a disease that affects both brain and behavior.
Formed with SAMHSA to reduce the gap between research results and treatment.